Results 31 to 40 of about 44,618 (265)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Popularization of Science in Brazil: getting onto the public agenda, but how? [PDF]

open access: yesJCOM: Journal of Science Communication, 2008
The importance the Brazilian government has given in the last few years to the dissemination of science points out the necessity of a more discerning analysis about the establishment of this subject on the public agenda and the related public policies ...
Márcia Tait Lima   +2 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Users and peers. From citizen science to P2P science [PDF]

open access: yesJCOM: Journal of Science Communication, 2010
This introduction presents the essays belonging to the JCOM special issue on User-led and peer-to-peer science. It also draws a first map of the main problems we need to investigate when we face this new and emerging phenomenon.
Alessandro Delfanti
doaj  

Community science: A typology and its implications for governance of social-ecological systems

open access: yesEnvironmental Science & Policy, 2020
Abstract There is an increasing recognition globally of the role to be played by community science –scientific research and monitoring driven and controlled by local communities, and characterized by place-based knowledge, social learning, collective action and empowerment.
Anthony Charles   +3 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Popularization of Science in Brazil: getting onto the public agenda, but how? (Portuguese original version) [PDF]

open access: yesJCOM: Journal of Science Communication, 2008
The importance the Brazilian government has given in the last few years to the dissemination of science points out the necessity of a more discerning analysis about the establishment of this subject on the public agenda and the related public policies ...
Márcia Tait Lima   +2 more
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Science and society of knowledge [PDF]

open access: yesJCOM: Journal of Science Communication, 2007
Probably among the first to deal with it, nearly sixty years ago, Norbert Wiener, the founding father of cybernetics (The human use of human beings. Cybernetics and Society, Houghton Mifflin Company, London, 1950), prefigured its opportunities, as well ...
Pietro Greco
doaj  

Let's govern together! SCOSS: community in action for Open Science

open access: yes, 2021
This poster explains the governance structure of the Global Sustainability Coalition for Open Science Services (SCOSS), focusing on good governance principles: transparency, trust, diversity, equity, and inclusion.
openaire   +2 more sources

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