Results 41 to 50 of about 44,618 (265)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Boiarsky draws from research in rhetoric, linguistics, technical communication, and psychology for a new approach at risk communication and the communication skills necessary for dealing with environmental and technological problems that could lead to major crises.--Provided by publisher.
Boiarsky, Carolyn R., author +1 more
openaire +4 more sources
Science and society of knowledge (Italian original version) [PDF]
Probably among the first to deal with it, nearly sixty years ago, Norbert Wiener, the founding father of cybernetics (The human use of human beings. Cybernetics and Society, Houghton Mifflin Company, London, 1950), prefigured its opportunities, as well ...
Pietro Greco
doaj
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Systematically sceptical (Italian original version) [PDF]
One can no longer rely on the presumption that scientists comply with the Mertonian value of disinterest and assume that they always tell the truth when spreading the results of their research projects.
Pietro Greco
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Systematically sceptical [PDF]
One can no longer rely on the presumption that scientists comply with the Mertonian value of disinterest and assume that they always tell the truth when spreading the results of their research projects.
Pietro Greco
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
CNRS researchers' popularization activities: a progress report (French original version) [PDF]
We have analyzed the popularization activities undertaken by ten thousand CNRS researchers by means of their annual reports for the years 2004, 2005 and 2006.
Yves Croissant, Pablo Jensen
doaj
Decisions by new Ontario government worry science and health care communities [PDF]
Doug Ford has been premier of Ontario for less than two weeks, but his Progressive Conservative party has already made changes that have raised alarm in health care and scientific circles. On June 30, the day after the party took power, the province’s new minister of health and long-term care,
openaire +1 more source

