Results 51 to 60 of about 2,277,474 (318)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Negotiating Care Work: Gendered Network Structures of Pandemic Care Discourses on Twitter in Germany

Media and Communication, 2023
Precarious conditions of care work are contested and deeply gendered issues all over the globe. The Covid-19 pandemic both intensifies the (national) care crises and makes care work more visible as a public issue.
Miriam Siemon, Wolfgang Reißmann
doaj   +1 more source

COM412: Photo communication / Faculty of Communication and Media Studies [PDF]

, 2013
The course is offered as a compulsory course and it is aimed at preparing students with practical and theoretical knowledge of shooting and composing photographs using Single Lens Reflex (SLR) cameras.
UiTM, Faculty of Communication and Media Studies
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

ENGLISH- STEREOTYPING OF ISLAM AND MUSLIMS IN HOLLYWOOD MOVIES: AN ANALYSIS OF REPRESENTATION

دی اسکالر, 2020
Hollywood movies are very popular in most nations around the world and the viewers of these countries turn to Hollywood blockbusters for entertainment purposes.
Muhammad Yousaf, Nauman Sial, Adnan Munawar, Muhammad Shahzad   +3 more
doaj  

COM269: Multiplatform interactive design / Faculty of Communication and Media Studies [PDF]

, 2022
This course is primarily to introduce and prepare students with the knowledge and skills in identifying and applying the technologies that is appropriate to multimedia applications.
UiTM, Faculty of Communication and Media Studies
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Teaching journalism and mass communication during the COVID-19 pandemic: Zambian lecturers’ experiences of the transition to online instruction

Discover Education
The global outbreak of the Corona Virus Disease (COVID-19) brought a myriad of challenges to higher education. At tertiary institutions worldwide, the closure of campuses and the migration to online instruction came as an unplanned consequence for ...
Carole Phiri-Chibbonta, Roberta Muchangwe, Elastus Mambwe   +2 more
doaj   +1 more source