Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Barriers to Obtaining Informed Consent Among Surgeons: A Cross-sectional Study at a Tertiary Care Hospital in Dakshina Kannada, India [PDF]
Introduction: Informed consent involves the patient in shared decision-making by providing adequate information about the disease, recommended plan of care and authorisation to proceed.
Mohammad Zahed Khan Gooty +2 more
doaj +1 more source
System Evolution Barriers and How to Overcome Them! [PDF]
Creating complex systems from scratch is time consuming and costly, therefore a strategy often chosen by companies is to evolve existing systems. Yet evolving a system is also complicated. Complex systems are usually the result of multidisciplinary teams,
Bonnema, G. Maarten, Borches, P. Daniel
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Productivity, Factor Accumulation and Social Networks: Theory and Evidence [PDF]
The paper analyses how barriers to communication across social groups affect economy-wide productivity and factor accumulation. Using a dynamic model of an economy that includes a reproducible capital stock (physical or human) and effective labour ...
P. Dorian Owen +2 more
core +3 more sources
COMMUNICATION: DEFINITION, TYPES OF COMMUNICATION AND BARRIERS OF COMMUNICATION
In this article author considers genesis of a concept of communication, and also the modern domestic theories describing this phenomenon of communication.
P. Yakupov
doaj
Reframing social exclusion from science communication: Moving away from 'barriers' towards a more complex perspective [PDF]
Science communication is an increasingly important field of activity,research and policy. It should not be assumed however, that science communication practices provide equitable and empowering opportunities for everyone.
Dawson, E
core
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
COMMUNICATION: DEFINITION, TYPES OF COMMUNICATION AND BARRIERS OF COMMUNICATION
In this article author considers genesis of a concept of communication, and also the modern domestic theories describing this phenomenon of communication.
P. Yakupov
doaj
Comparison of the Psychological Characteristics of Adaptation in Orphan Students of Initial Learning Stage to Adaptation Potential in Students Brought up in Families [PDF]
We present a study of psychological characteristics of preadult orphans, their psychological adaptation to the conditions of learning in high school compared to the norm population (students living in family).
Zamorueva V.V.,
doaj

