Results 61 to 70 of about 5,392,741 (341)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Influence of barriers to organizational communication on employees’ work-life balance

open access: yes, 2022
Link to publisher's homepage at https://johdec.unimap.edu.my/Work From Home (WFH) has been implemented for more than one and a half years in Jakarta, yet only 14% of employees in Jakarta were very satisfied with their quality of life.
Elly Yuliawati   +1 more
core  

Rapid and Long-term Measures for Prevention and Mitigation of Communication Barriers in Production Networks

open access: yesProceedings of the Conference on Production Systems and Logistics, 2020
Due to the constantly increasing complexity and dynamic of modern production networks within value chains, effective communication between the individual corporations is required.
Kelber, Michael   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Barriers to Obtaining Informed Consent Among Surgeons: A Cross-sectional Study at a Tertiary Care Hospital in Dakshina Kannada, India [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Informed consent involves the patient in shared decision-making by providing adequate information about the disease, recommended plan of care and authorisation to proceed.
Mohammad Zahed Khan Gooty   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

ICT skills acquisition by older people: motivations for learning and barriers to progression [PDF]

open access: yes, 2013
This paper reports findings from one strand of an extensive research project investigating digital engagement of older people and the risks to sustained usage of information and communication technologies (ICTs).
Sandhu, J, Ramondt, L, Damodaran, L
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Comparison of the Psychological Characteristics of Adaptation in Orphan Students of Initial Learning Stage to Adaptation Potential in Students Brought up in Families [PDF]

open access: yesПсихологическая наука и образование (2007. Online), 2014
We present a study of psychological characteristics of preadult orphans, their psychological adaptation to the conditions of learning in high school compared to the norm population (students living in family).
Zamorueva V.V.,
doaj  

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