Results 61 to 70 of about 1,496,354 (307)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

African-American patients with cancer Talking About Clinical Trials (TACT) with oncologists during consultations: evaluating the efficacy of tailored health messages in a randomised controlled trial—the TACT study protocol [PDF]

open access: yes, 2016
Introduction Low rates of accrual of African-American (AA) patients with cancer to therapeutic clinical trials (CTs) represent a serious and modifiable racial disparity in healthcare that impedes the development of promising cancer therapies.
Alpert, J   +8 more
core   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Articulating Roles and Responsibilities in the Transition Planning Process: A Practice Aimed at Figuring Out How to Work Together [PDF]

open access: yes, 2004
It is clear that the intention of the Individual with Disabilities Education Act require both the Education Agency and the Vocational Rehabilitation Agency (VESID, in New York State) to jointly participate in the development of transition plans for ...
Golden, Thomas P., Murphy, Marianne
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Professionals' and Intercultural Mediators' Perspectives on Communication With Ukrainian Refugees in the Czech Healthcare System

open access: yesHealth Expectations
Introduction A growing body of research is examining how healthcare systems are responding to the increasing numbers of migrants and the resulting superdiversity of patients.
Jolana Kopsa Těšinová   +4 more
doaj   +1 more source

Communication Management at International Shakespeare Festival Craiova. Cross-cutting perspectives [PDF]

open access: yesSocial Sciences and Education Research Review
This analysis aims to describe how the identity of the Craiova International Shakespeare Festival has been built over time. It will trace the communication patterns, the diversification of audience categories and the democratization of the festival's ...
Xenia Negrea
doaj   +1 more source

No sign of harm : issues for disabled children communicating about abuse [PDF]

open access: yes, 2001
While all children may be the victims of abuse, disabled children are particularly vulnerable. This paper explores the views of professionals working with children using alternative/augmented communication systems on the issues relating to communication ...
Authier   +26 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Challenges and Strategies for Building and Maintaining Effective Preceptor-Preceptee Relationships among Nurses

open access: yesSultan Qaboos University Medical Journal, 2014
Objectives: This study aimed to determine the challenges encountered and strategies used by nurse preceptors to build effective professional relationships during the preceptorship of final year nursing students.
Gerald A. Matua   +3 more
doaj  

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