Results 91 to 100 of about 5,154,741 (248)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Coded Modulation Assisted Iterative Parallel Interference Cancellation Aided CDMA

open access: yes, 2003
In this contribution we investigate Trellis Coded Modulation (TCM) and Turbo Trellis Coded Modulation (TTCM) assisted iterative parallel interference cancellation aided CDMA schemes.
Ng, S.X., Hua, Wei, Hanzo, L.
core   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

One-Photon-Interference Quantum Secure Direct Communication

open access: yesEntropy
Quantum secure direct communication (QSDC) is a quantum communication paradigm that transmits confidential messages directly using quantum states. Measurement-device-independent (MDI) QSDC protocols can eliminate the security loopholes associated with ...
Xiang-Jie Li   +4 more
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song   +10 more
wiley   +1 more source

Adaptive modulation schemes for optical wireless communication systems [PDF]

open access: yes
High-speed wireless optical communication links have become more popular for personal mobile applications. This is a consequence of the increasing demand from the personal information service boom.
Zeng, Yu
core  

Research on Packet Loss Caused by EMC Interference in Train Network Control System

open access: yes机车电传动, 2017
EMI on the train will cause random interference to the communication of the train network control system, and then cause the packet loss of the network communication.
LI Changxian   +3 more
doaj  

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Communication and interference coordination

open access: yes, 2014
We study the problem of controlling the interference created to an external observer by a communication processes. We model the interference in terms of its type (empirical distribution), and we analyze the consequences of placing constraints on the ...
Skoglund, Mikael   +8 more
core   +1 more source

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