Results 101 to 110 of about 5,192,924 (250)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Nonlinear Mutation Frequency Interference Detection Algorithm for All Optical Communication Networks

Guangtongxin yanjiu
【Objective】When analyzing the nonlinear mutation frequency interference problem in all optical communication networks, interference detection mainly relies on estimating channel covariance directly, without expanding network communication signal ...
AN Ning
doaj  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Research on Anti-Single-Frequency Interference Ability of Underwater Acoustic DSSS Communication System with Short-Period PN Sequences

Applied Sciences
To address the inability to quantitatively analyze the performance of the direct sequence spread spectrum (DSSS) communication system in the presence of short-period pseudo-noise (PN) sequences, this study derives the interference components resulting ...
Xiaowei Wang, Yong Wei, Qi Ma
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Joint Space-Time Interference Cancellation for mmWave Active Array SDR Platforms in Coexistent Sensing and Communication Systems

IEEE Access
This paper investigates the interference issue between sensing and communication millimeter-wave (mmWave) active arrays, such as the sensing array (SA) and communication array (CA), which share the same time and frequency resources at a base station (BS)
Juinn-Horng Deng, Yuanzhang Xiao, Meng-Lin Ku, Soo Yong Lim, Jill S. K. Nakatsu, Magdy F. Iskander   +5 more
doaj   +1 more source

Precipitation scatter interference between space and terrestrial communication systems [PDF]

, 1967
Transmission loss from precipitation scatter interference between space and earth communication ...
Altman, F. J.
core  

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Dual‑module Interference Cancellation Scheme for UCCA‑OAM Communication System

Shuju Caiji Yu Chuli
Orbital angular momentum （OAM） is a technique that provides additional degrees of freedom to improve the spectral efficiency of wireless communication.
LI Ting, SHEN Mingyu, ZHANG Chunjie, XIE Peizhong   +3 more
doaj   +1 more source