Results 61 to 70 of about 5,261,043 (276)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Context-aware Cluster Based Device-to-Device Communication to Serve Machine Type Communications

, 2017
Billions of Machine Type Communication (MTC) devices are foreseen to be deployed in next ten years and therefore potentially open a new market for next generation wireless network. However, MTC applications have different characteristics and requirements
Lianghai, Ji, Man, Liu, Schotten, Hans D.   +2 more
core   +1 more source

CORBYS cognitive control architecture for robotic follower [PDF]

, 2013
In this paper the novel generic cognitive robot control architecture CORBYS is presented. The objective of the CORBYS architecture is the integration of high-level cognitive modules to support robot functioning in dynamic environments including ...
Badii, Atta, Glackin, Cornelius, Khan, Ali, Leu, Adrian, Polani, D., Raval, Rajkumar, Ristic-Durrant, Danijela, Salge, Christoph, Slavnic, Sinisa   +8 more
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Mechanical characteristics of porous SUS630 using additive manufacturing

Journal of Advanced Mechanical Design, Systems, and Manufacturing
Porous metal materials are constructed using selective laser melting (SLM). Porous metals exhibit different physical and mechanical properties, depending on the building conditions.
Tetsuya TASHIRO, Tohma KANAO, Yuya NAGATA, Makoto TSUBOTA   +3 more
doaj   +1 more source

Security issues and system structure of internet of vehicles

网络与信息安全学报, 2016
Instead of focusing on concrete security requirements of each IOV applying scenario,the architecture characteristics of the IOV networking systems were summarized,and the main security problems were extracted by analyzing the connotation and network ...
Liang-min WANG, Ting-ting LI, Long CHEN
doaj   +1 more source

Intuition in Healthcare Communication Practices: Initial Findings from a Qualitative Inquiry [PDF]

, 2017
This brief paper reports on how healthcare providers negotiate stages of care and communication by using intuition. This focus shifts attention away from the product-patient records-and towards the process of medical communication. To support this claim,
Angeli, Elizabeth L., Campbell, Lillian
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Bridging the digital divide: exploring the challenges and solutions for digital exclusion in rural South Africa

Discover Global Society
Digital exclusion remains a pervasive challenge in rural South Africa, reinforcing existing socio-economic disparities, with communities such as Mkatazo village in the Eastern Cape experiencing compounded challenges, including inadequate infrastructure ...
Gardner Mwansa, Matipa Ricky Ngandu, Zolisa Mkwambi   +2 more
doaj   +1 more source