Results 91 to 100 of about 2,327,995 (319)

AISR Connections, Fall 2011 (2011-2012 Orientation Issue) [PDF]

open access: yes, 2011
Yearly publication of AISR Connections for 2011-2012. Issue includes: FACT Program Incorporates iPads Classroom Technologies & Videoconferencing Jefferson Digital Commons Posts Half Million Downloads The mission of Academic & Instructional Support ...
AISR,
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Strategy for Individuals Distribution by Incident Nodes Participation in Star Topology of Distributed Evolutionary Algorithms

open access: yesCybernetics and Information Technologies, 2016
One of the strongest advantages of Distributed Evolutionary Algorithms (DEAs) is that they can be implemented in distributed environment of heterogeneous computing nodes. Usually such computing nodes differ in hardware and operating systems.
Balabanov Todor   +2 more
doaj   +1 more source

Mapping the Money in Public Media [PDF]

open access: yes, 2008
Provides an overview of emerging "user-centric" business models for public media that utilize the interactivity of digital technologies as a way to integrate content, communication, commerce, and community through participatory media ...
Diane Mermigas
core  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Experimental Implementation of Enhanced Security Coherent One-Way Quantum Key Distribution

open access: yesIEEE Access
Coherent One-Way (COW) is a simple and widely utilized quantum key distribution (QKD) protocol, favored in both experimental and commercial applications. In this paper, we compare the information that an eavesdropper, Eve, can acquire in both the 2-decoy
Amirhosein Dadahhani   +6 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

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