Results 41 to 50 of about 5,411,944 (299)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transition time between long-term conditions among childbearing women in England: a nationwide observational analysis

Family Medicine and Community Health
Objective To examine transition times between long-term conditions (LTCs) and their associated determinants among childbearing women.Design A population-based cohort study.
Adeniyi Fagbamigbe, Amanda Rodrigues Amorim Adegboye, Sobia Ambreen, Abiodun Adanikin   +3 more
doaj   +1 more source

Governor Rendell signs declaration against government spending on sweatshop goods [PDF]

, 2008
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
International Labor Rights Forum, Sweatfree Communities   +1 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Microbial core communities in activated sludge plants are strongly affected by immigration and geography

Environmental Microbiome
Background The microbiota in wastewater treatment plants (WWTPs) and incoming wastewater is critical for the treatment process, the preservation of natural ecosystems and human health, and for the recovery of resources and achievement of sustainability ...
Sofie Zacho Vestergaard, Giulia Dottorini, Miriam Peces, Admir Murguz, Morten Kam Dahl Dueholm, Marta Nierychlo, Per Halkjær Nielsen   +6 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Ecophysiology and niche differentiation of three genera of polyphosphate-accumulating bacteria in a full-scale wastewater treatment plant

mSystems
Polyphosphate-accumulating organisms (PAOs) are the main bacteria responsible for phosphorus removal and recovery in full-scale wastewater treatment plants (WWTPs).
Z. Kondrotaite, J. Petersen, C. Singleton, M. Peces, F. Petriglieri, T. B. N. Jensen, M. Sereika, A. O. H. Daugberg, M. Wagner, M. K. D. Dueholm, P. H. Nielsen   +10 more
doaj   +1 more source

New study exposes failure in Wal-Mart\u27s auditing program, finds sweatshop conditions in Bangladesh factory [PDF]

, 2008
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
International Labor Rights Forum, Sweatfree Communities   +1 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Genomic and in Situ Analyses Reveal the Micropruina spp. as Abundant Fermentative Glycogen Accumulating Organisms in Enhanced Biological Phosphorus Removal Systems

Frontiers in Microbiology, 2018
Enhanced biological phosphorus removal (EBPR) involves the cycling of biomass through carbon-rich (feast) and carbon-deficient (famine) conditions, promoting the activity of polyphosphate accumulating organisms (PAOs).
Simon J. McIlroy, Cristobal A. Onetto, Bianca McIlroy, Florian-Alexander Herbst, Morten S. Dueholm, Rasmus H. Kirkegaard, Eustace Fernando, Søren M. Karst, Marta Nierychlo, Jannie M. Kristensen, Kathryn L. Eales, Paul R. Grbin, Reinhard Wimmer, Per Halkjær Nielsen   +13 more
doaj   +1 more source