Results 51 to 60 of about 4,149,804 (299)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Age-friendly communities : frequently asked questions
"September 2019."; Includes bibliographical referencesWhat is an age-friendly community? -- What are the build environment elements of an age-friendly community? -- What is aging in place? -- How can communities support aging in place?
core
No abstract available.
Building Healthy Academic Communities BHAC Journal
doaj +3 more sources
Polyphosphate-accumulating organisms (PAOs) are the main bacteria responsible for phosphorus removal and recovery in full-scale wastewater treatment plants (WWTPs).
Z. Kondrotaite +10 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Background New Mexico is the first state in the U.S. to implement a comprehensive, statewide assessment of children’s developmental health in tandem with sweeping early childhood policy reforms.
Judith L. Perrigo +5 more
doaj +1 more source
Objective Young Indigenous people are vulnerable to lateral violence, where negative feelings and behaviours are directed towards members within their own oppressed group. Lateral empowerment, in contrast, is where young people can promote resilience and
Yvonne Clark +9 more
doaj +1 more source

