Results 251 to 260 of about 146,984 (316)

Clinical outcome and costs of nosocomial and community-acquired Staphylococcus aureus bloodstream infection in haemodialysis patients

open access: bronze, 2006
Wolfgang Greiner   +5 more
openalex   +1 more source

SAAP‐148 oligomerizes into a hexamer forming a hydrophobic inner core

open access: yesChemBioChem, Accepted Article.
Human cathelicidin LL‐37 is a widely studied antimicrobial 37‐mer peptide with various ascribed functions, that serves as a template for designing novel peptides. Its derivative, the 24‐mer SAAP‐148, is highly effective in vitro in eradicating multidrug‐resistant bacteria, persistent cells, and biofilms, without inducing resistance.
Nermina Malanovic   +15 more
wiley   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok   +5 more
wiley   +1 more source

Addressing Data Point Homogeneity and Annotation Challenges to Enhance Data‐Driven Approaches: The S. aureus NorA Efflux Pump Case Study

open access: yesChemMedChem, EarlyView.
Analysis of publicly available data on the biological activities associated with the Staphylococcus aureus NorA efflux pump shows critical inconsistencies and homogeneity issues that hinder the discovery of NorA inhibitors. Based on the tips extracted from this analysis, a standardized experimental pipeline is proposed to improve data quality and ...
Andrea Astolfi   +6 more
wiley   +1 more source

GDF15 Analogues Acting as GFRAL Ligands

open access: yesChemMedChem, EarlyView.
Considering the great importance of the GDF15/GRAL/RET signalling pathway, this review focuses on GDF15‐derived analogues able to act either as GFRAL agonists or antagonists, investigating their possible pharmacological applications in the treatment of GDF15‐related conditions, such as obesity and diabetes (agonist), or cancer‐induced nausea and ...
Andrea Di Santo   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy