Results 31 to 40 of about 146,984 (316)
An age-of-infection model with both symptomatic and asymptomatic infections [PDF]
We formulate a general age-of-infection epidemic model with two pathways: the symptomatic infections and the asymptomatic infections. We then calculate the basic reproduction number $\mathcal{R}_0$ and establish the final size relation. It is shown that the ratio of accumulated counts of symptomatic patients and asymptomatic patients is determined by ...
arxiv
On the Universality of Jordan Centers for Estimating Infection Sources in Tree Networks [PDF]
Finding the infection sources in a network when we only know the network topology and infected nodes, but not the rates of infection, is a challenging combinatorial problem, and it is even more difficult in practice where the underlying infection spreading model is usually unknown a priori. In this paper, we are interested in finding a source estimator
arxiv +1 more source
Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia
Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo+4 more
wiley +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns+2 more
wiley +1 more source
Background and Objectives: Legionnaires’ disease (LD) is an acute respiratory disease with increasing annual numbers of reported domestic and global cases.
Hae-Deun Noh+3 more
doaj +1 more source
Biomarkers in community-acquired pneumonia: A state-of-the-art review
Community-acquired pneumonia (CAP) exhibits mortality rates, between 20% and 50% in severe cases. Biomarkers are useful tools for searching for antibiotic therapy modifications and for CAP diagnosis, prognosis and follow-up treatment. This non-systematic
Renato Seligman+5 more
doaj +1 more source
Globally, multidrug-resistant bacteria affects wound infections, both hospital-acquired infections and community-acquired infections. The main isolates cultured from 607 subjects with wound infections were methicillin-resistant Staphylococcus aureus ...
Hashem A. Abu-Harirah+4 more
doaj +1 more source
Spatially dense stochastic epidemic models with infection-age dependent infectivity [PDF]
We study an individual-based stochastic spatial epidemic model where the number of locations and the number of individuals at each location both grow to infinity. Each individual is associated with a random infection-age dependent infectivity function. Individuals are infected through interactions across the locations with heterogeneous effects.
arxiv
Efflux‐mediated resistance compromises antibiotic efficacy, yet rapid detection remains elusive. This study presents a novel phenazinium‐based diagnostic molecule for quantifying bacterial efflux levels in Gram‐positive pathogens. The optimized compound enables precise, real‐time efflux assessment using fluorescence and colorimetric techniques ...
Mrunal Patil+15 more
wiley +1 more source
Abstract Objectives This study examines the associations between water insecurity, self‐reported physical health, and objective measures of biological health among 225 Awajún adults (107 women; 118 men) living in the Peruvian Amazon, a “water‐abundant” region.
Paula Skye Tallman+3 more
wiley +1 more source