Results 31 to 40 of about 222,349 (259)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mathematical modelling of community acquired antibiotic resistant infections

Informatics in Medicine Unlocked
Antibiotic usage in hospitals is considered the major driver of the emergence of antibiotic resistance where selection of multiply resistant strains is most common. However, massive antibiotic consumption occurs in the community. We formulate and analyse
Josiah Mushanyu
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Biomarkers in community-acquired pneumonia: A state-of-the-art review

Clinics, 2012
Community-acquired pneumonia (CAP) exhibits mortality rates, between 20% and 50% in severe cases. Biomarkers are useful tools for searching for antibiotic therapy modifications and for CAP diagnosis, prognosis and follow-up treatment. This non-systematic
Renato Seligman, Luis Francisco Ramos-Lima, Vivian do Amaral Oliveira, Carina Sanvicente, Elyara F Pacheco, Karoline Dalla Rosa   +5 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Drug resistance in community-acquired respiratory tract infections: role for an emerging antibacterial

Infection and Drug Resistance, 2010
Lorenzo Aguilar1, María-José Giménez1, José Barberán21Microbiology Department, School of Medicine, University Complutense, Madrid; 2Infectious Diseases Department, Hospital Central de la Defensa ...
Lorenzo Aguilar, María-José Giménez, José Barberán   +2 more
doaj  

Extended-Spectrum β-Lactamase and Carbapenemase-Producing Gram-Negative Bacteria and Associated Factors Among Patients Suspected of Community and Hospital-Acquired Urinary Tract Infections at Ayder Comprehensive Specialized Hospital, Tigrai, Ethiopia

Infection and Drug Resistance, 2023
Mulu Gebretsadik Gebremedhin,1 Yemane Weldu,2 Atsebaha Gebrekidan Kahsay,2 Gebrecherkos Teame,3 Kelemework Adane4 1Ayder Comprehensive Specialized Hospital, Mekelle University, Mekelle, Tigrai, Ethiopia; 2Department of Medical Microbiology and Immunology,
Gebremedhin MG, Weldu Y, Kahsay AG, Teame G, Adane K   +4 more
doaj  

Neutrophil-to-lymphocyte ratio: a potential supportive marker for elderly community-acquired bloodstream infections—a retrospective study [PDF]

PeerJ
Background Exploring the value of the neutrophil/lymphocyte ratio (NLR) as a potential supportive marker in community-acquired bloodstream infection in elderly patients.
Peijuan Li, Jiulin Zhang, Kun Chen, Qianqian Pei, Mengxi Ding, Chunmei Wang   +5 more
doaj   +2 more sources

Mixed community-acquired lower respiratory tract infections [PDF]

Current Infectious Disease Reports, 2007
Although mixed infections are known to be clinically relevant in conditions such as nosocomial pneumonia and ventilator-related pneumonia, it is increasingly recognized that a substantial number of community-acquired lower respiratory tract infections may also be attributed to more than one pathogenic organism. A better definition of the true incidence
P. Tarsia, S. Aliberti, M. Pappalettera, F. Blasi   +3 more
openaire   +4 more sources