Results 51 to 60 of about 7,021,826 (278)

Astropy: A community Python package for astronomy [PDF]

open access: yes, 2013
We present the first public version (v0.2) of the open-source and community-developed Python package, Astropy. This package provides core astronomy-related functionality to the community, including support for domain-specific file formats such as ...
T. P. Robitaille   +43 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

A decade of perinatal mortality in Pakistan: Systematic review of patterns and challenges (2013–2022)

open access: yesJournal of Taibah University Medical Sciences
الملخص: أهداف البحث: تعرف منظمة الصحة العالمية الوفيات حول الولادة بأنها ''وفاة طفل بين 28 أسبوعا من الحمل فصاعدا وحتى الأيام السبعة الأولى من حياته''.
N. Shahid, M.Phil. Statistics   +4 more
doaj   +1 more source

The scarlet letter of “post-truth”: the sunset boulevard of communication

open access: yesChurch, Communication and Culture, 2019
In this paper post-truth mechanisms in discourse are taken into account and the attempt is made to understand how language is used in communication characterized by post-truth.
Giovanni Gobber
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Virtual Community: Homesteading on the Electronic Frontier

open access: yes, 1996
A review of The Virtual Community: Homesteading on the Electronic Frontier, by Howard Rheingold. Creative Commons License This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.
D. Hindman
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Community Structure and Crime: Testing Social-Disorganization Theory

open access: yesAmerican Journal of Sociology, 1989
Shaw and McKay's influential theory of community social disorganization has never been directly tested. To address this, a community-level theory that builds on Shaw and McKay's original model is formulated and tested.
R. Sampson, W. Groves
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy