Results 41 to 50 of about 6,130,402 (300)
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
mBio, 2013 The processes and mechanisms of community assembly and its relationships to community functioning are central issues in ecology. Both deterministic and stochastic factors play important roles in shaping community composition and structure, but the ...
Jizhong Zhou +9 more
doaj +1 more source
Species traits and connectivity constrain stochastic community re-assembly
, 2017 All communities may re-assemble after disturbance. Predictions for re-assembly outcomes are, however, rare. Here we model how fish communities in an extremely variable Australian desert river re-assemble following episodic floods and drying.
Balcombe, Stephen R +12 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Divergent Abiotic Stressors Drive Grassland Community Assembly of Tibet and Mongolia Plateau
Frontiers in Plant Science, 2022 Multiple ecological processes simultaneously govern community assembly, but it remains unclear how abiotic stressors regulate the relative importance of these processes among different biogeographic regions.
Jianming Wang +7 more
doaj +1 more source
Community assembly rules affect the diversity of expanding communities [PDF]
Ecology and Evolution, 2014 AbstractDespite centuries of interest in species range limits, few studies have taken a whole community into consideration. Actually, multiple species may simultaneously respond to environmental changes, for example, global warming, leading a series of dynamical communities toward the advancing front.
Peng, Zechen, Zhou, Shurong
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Soil Biota as Drivers of Plant Community Assembly
, 2018 Evidence is accumulating that belowground soil organisms are strong drivers of the aboveground plant community. In this chapter, we examine how soil communities influence plant community assembly through priority effects, soil legacy effects, and niche ...
Sveriges lantbruksuniversitet. +1 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Functional attractors in microbial community assembly
Cell Systems, 2022 For microbiome biology to become a more predictive science, we must identify which descriptive features of microbial communities are reproducible and predictable, which are not, and why. We address this question by experimentally studying parallelism and convergence in microbial community assembly in replicate glucose-limited habitats.
Estrela, Sylvie +8 more
openaire +4 more sources