Results 71 to 80 of about 1,651,191 (277)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Resorting to Context-Aware Background Knowledge for Unveiling Semantically Related Social Media Posts

open access: yesIEEE Access, 2022
Social media networks have become a prime source for sharing news, opinions, and research accomplishments in various domains, and hundreds of millions of posts are announced daily.
Ahmad Sakor   +2 more
doaj   +1 more source

Deep Community Detection [PDF]

open access: yesIEEE Transactions on Signal Processing, 2015
15 pages, 13 figures, journal submission and supplementary file (Figures 11-13), to appear in IEEE Transactions on Signal ...
Chen, Pin-Yu, Hero, Alfred O.
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Local multiresolution order in community detection

open access: yes, 2014
Community detection algorithms attempt to find the best clusters of nodes in an arbitrary complex network. Multi-scale ("multiresolution") community detection extends the problem to identify the best network scale(s) for these clusters.
Arenas A   +22 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

A fast and intuitive method for calculating dynamic network reconfiguration and node flexibility

open access: yesFrontiers in Neuroscience, 2023
Dynamic interactions between brain regions, either during rest or performance of cognitive tasks, have been studied extensively using a wide variance of methods.
Narges Chinichian   +14 more
doaj   +1 more source

Description-Driven Community Detection

open access: yesACM Transactions on Intelligent Systems and Technology, 2014
Traditional approaches to community detection, as studied by physicists, sociologists, and more recently computer scientists, aim at simply partitioning the social network graph. However, with the advent of online social networking sites, richer data has become available: beyond the link information, each user in the network is annotated ...
Pool, Simon   +2 more
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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