Results 31 to 40 of about 343,697 (224)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Early experiences as intrinsic, extrinsic, and interpersonal motivators that influence first year medical school students’ career choice for medicine: a qualitative study

Discover Education
Background Research is needed to better understand the early experiences that motivate and influence students to choose careers in medicine. Methods We addressed this research gap with an exploratory qualitative study that included four focus groups ...
Jessica St. Louis, Megan Pasquantonio-Pierce, Emorcia V. Hill, Joan Y. Reede, Jeffrey N. Katz   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Nature prescribing: emerging insights about reconciliation-based and culturally inclusive approaches from a tricultural community health centre

Health Promotion and Chronic Disease Prevention in Canada
This commentary highlights the importance of social and nature prescribing programs reflecting culturally diverse perspectives and practices. Creating and holding space for Indigenous and other worldviews should be a key priority of nature prescribing, a
Anita Vaillancourt, Rebecca Barnstaple, Natalie Robitaille, Taylor Williams   +3 more
doaj   +1 more source

Communities’ views, attitudes and recommendations on community-based education of undergraduate Health Sciences students in South Africa: A qualitative study

African Journal of Primary Health Care & Family Medicine, 2013
Background: Medical and Health Sciences students in South Africa undertake community-based education (CBE). Health professionals based at host sites are jointly responsible for training of these students in conjunction with university staff.
Langalibalele H. Mabuza, Paula Diab, Stephen J. Reid, Busisiwe E. Ntuli, Penelope S. Flack, Ratie Mpofu, Priscilla S. Daniels, Tracy-Ann Adonis, Mandisa Cakwe, Mugambi W. Karuguti, Ngkatiseng Molefe   +10 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Operational strategies for achieving comprehensive cancer center community outreach and engagement objectives: impact and logic models

Archives of Public Health
Background The National Cancer Institute’s (NCI) Cancer Center Support Grants (CCSGs) encourages Cancer Centers to address health disparities and reduce the cancer burden in their Catchment Area (CA) through an organized Community Outreach and Engagement
Folakemi T. Odedina, Manisha Salinas, Monica Albertie, Doug Murrell, Kristin Munoz   +4 more
doaj   +1 more source

PIDapalooza – the open festival for persistent identifiers

Insights: The UKSG Journal, 2017
In 2016 three persistent identifier (PID) organizations – Crossref, DataCite and ORCID – together with California Digital Library organized PIDapalooza, the first open festival for PIDs.
Alice Meadows
doaj   +1 more source

Breastfeeding rates are high in a prenatal community support program targeting vulnerable women and offering enhanced postnatal lactation support: a prospective cohort study

International Journal for Equity in Health, 2021
Background In Canada, 91% of all mothers initiate breastfeeding, but 40–50% stop by 6 months and only 34% breastfeed exclusively for 6 months, with lower rates among socially and/or economically vulnerable women.
Jane Francis, Alison Mildon, Stacia Stewart, Bronwyn Underhill, Samantha Ismail, Erica Di Ruggiero, Valerie Tarasuk, Daniel W. Sellen, Deborah L. O’Connor   +8 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source