Results 61 to 70 of about 197,302 (301)
Genetic Research in Native Communities [PDF]
Progress in Community Health Partnerships: Research, Education, and Action, 2008 People are living longer because of advances made through biomedical research. The challenge in genetic research on indigenous peoples is that it raises a complex range of legal, ethical, social, spiritual, and political issues. The current research paradigm is one of paternalism and biocolonialism.
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Community structure and population genetics of Eastern Mediterranean polychaetes
Frontiers in Marine Science, 2014 Species and genetic diversity are often found to co-vary since they are influenced by external factors in similar ways. In this paper, we analyse the genetic differences of the abundant polychaete Hermodice carunculata (Pallas, 1776) during two ...
Giorgos eChatzigeorgiou +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Medical genetics services in the city of São Paulo, Brazil
, 2004 The city of S (a) over tildeo Paulo is located in the center of a metropolitan area with nearly 18 million inhabitants and 300,000 births/year. the currently existing medical genetics services are unable to meet the demand, due to their insufficient ...
Brunoni, D.
core +1 more source
Communicating genetic risk information [PDF]
British Medical Bulletin, 1999 It is envisaged that genetic information will be used, together with other types of information, to assess individuals' risks of developing a variety of common conditions. Such risk assessments will involve providing probabilistic information partly based upon results of genetic tests in order to facilitate behaviour change without causing excessive ...
openaire +3 more sources
Die gesondheidsvoorligtingsfunksie van die verpleegkundige met betrekking tot mensgenetika
Curationis, 1981 The nurse, as a key person in health services, has an essential role in health education regarding human and medical genetics. This education is given at both community and individual level.
Frieda Paton
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Frontiers in Pharmacology, 2017 Advances from pharmacogenetics (PGx) have not been implemented into health care to the expected extent. One gap that will be addressed in this study is a lack of reporting on clinical validity and clinical utility of PGx-tests.
Marleen E. Jansen +9 more
doaj +1 more source