Results 91 to 100 of about 643,526 (302)

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang   +7 more
wiley   +1 more source

A Prescription for Crime Prevention: Improving Youth Access to Effective Mental Health Approaches [PDF]

open access: yes, 2002
Examines youth mental health issues in California, focusing on at-risk youth and those already involved in the juvenile justice system.

core  

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo   +13 more
wiley   +1 more source

Distinct Biotypes of Visual Perception in Major Depressive Disorder

open access: yesAdvanced Science, EarlyView.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai   +13 more
wiley   +1 more source

The Utility of Trouble: Maximizing the Value of Our Human Services Dollars [PDF]

open access: yes, 2010
Outlines recommendations to standardize service delivery areas and consolidate area offices of the state's seven largest human services agencies, as well as to close antiquated institutions.
Michael J. Widmer   +3 more
core  

Why Didn't I Get a Payout? Understanding Farmer Choices, Index Insurance, and Basis Risk

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Index insurance, while heralded as a potential solution to alleviate poverty and food insecurity among agricultural households, has its own set of challenges, notably basis risk. Basis risk is the discrepancy between the insurance payout and losses incurred, posing a significant deterrent to the adoption of index insurance.
S. Lucille Blakeley   +4 more
wiley   +1 more source

An Assessment of Mental Health Services for Veterans in the State of Texas [PDF]

open access: yes, 2015
This report describes the complex challenges faced by veterans and their families in seeking, navigating, and attaining adequate mental health care in Texas.
Eaton, David   +3 more
core  

Enhancing Elderly Health Through Physical Activities: Insights From a Global Bibliometric Review, 1900–2023

open access: yesAGING MEDICINE, EarlyView.
Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang   +3 more
wiley   +1 more source

Role of School-Based Health Centers Under Universal Coverage for Children and Youth in California: Issues and Options [PDF]

open access: yes, 2007
Examines challenges of and provides suggestions for a universal model of health care delivery for all children and youth in California.
Nancy Torrey, Steve Rosenberg
core  

The Role of Artificial Intelligence in Medication Management for Older Adults: A Systematic Review

open access: yesAGING MEDICINE, EarlyView.
Artificial intelligence enhances medication management for older adults by improving adherence, personalizing treatment, and predicting risks. Despite benefits, challenges remain in usability, trust, ethics, and system integration. Successful adoption requires user‐centered design, ethical safeguards, and seamless healthcare integration to ensure safe,
Dipak Chandra Das   +9 more
wiley   +1 more source

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