Results 71 to 80 of about 746,198 (292)

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Psychiatry's Turbid Solution [PDF]

, 1997
Psychiatry?s generic concept of disorder has long served an important legitimizing function for the broad array of conditions for which individuals seek mental health treatment, regardless of their presumed causes.
Hinshaw, Stephen P., Richters, John E.
core   +1 more source

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

Advanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang, Ji Chen, Jinfeng Han, Wei Cheng, Jiang Qiu, Jianfeng Feng, Simon Eickhoff, Deniz Vatansever   +7 more
wiley   +1 more source

CASE MANAGEMENT – A PILLAR OF COMMUNITY PSYCHIATRY [PDF]

, 2010
This review is describing different models of case management, showing their similarities and differences with regards to the way they operate. Good relationship between patient and case manager, application of the biopsychosocial model, availability of ...
Lana Mužinić, Slađana Štrkalj Ivezić, Vanda Filipac   +2 more
core   +1 more source

Don’t turn your back on the symptoms of psychosis : a proof-of-principle, quasi-experimental public health trial to reduce the duration of untreated psychosis in Birmingham, UK [PDF]

, 2013
Background: Reducing the duration of untreated psychosis (DUP) is an aspiration of international guidelines for first episode psychosis; however, public health initiatives have met with mixed results.
A Malla, A Yung, AK Malla, B Lloyd-Evans, BB Sheitman, C Office, Charlotte Connor, Colin Palmer, D Linszen, Department of Health, H Goldman, H Krstev, HE Lester, Helen Lester, I Melle, Index of deprivation, J Prochaska, K Brunet, L Green, M Birchwood, M Marshall, Max Birchwood, Nick Freemantle, P Dolan, Paul Patterson, RJ Drake, S Carbone, S Rashid, SP Singh, SR Kay, Sunita Channa, Swaran Singh, TK Larsen   +32 more
core   +4 more sources

Advancing Dry Electroencephalography With Scalable, Soft, and Transcranial Magnetic Stimulation‐Compatible Ti3C2Tx MXene Electrodes for Research and Clinical‐Grade Applications

Advanced Science, EarlyView.
Dry soft Ti3C2Tx MXene electroencephalography (EEG) electrodes provide low impedance (2.1 ± 1.8 kΩ at 10 Hz), long‐term stability, and enable safe simultaneous EEG and transcranial magnetic stimulation (TMS). Across scalp sites, hair types, and recording paradigms, including steady state visual evoked potentials (SSVEP), clinical EEG, and mobile EEG ...
Sneha Shankar, Jakob Michiels, Ksenija Tasich, Ashley Koluda, Ryan Rich, Brian Erickson, Eugenia Angelopoulos, Francesca Cimino, Daryl Hurwitz, Raghav Garg, Spencer R. Averbeck, Doris Xu, Mariam Josyula, Nina Petillo, James J. Gugger, Kathryn A. Davis, John Medaglia, Flavia Vitale   +17 more
wiley   +1 more source

“It’s not just the residents who need to be motivated for activity”: a qualitative study of the perspectives of staff on providing activity support for people with psychiatric disabilities in supported housing in Sweden

Frontiers in Psychiatry
BackgroundThe goals for staff in Supported Housing for people with psychiatric disabilities include helping to develop the residents’ independence and self-confidence in activities.
Rosita Brolin, Carina Tjörnstrand, Mette Friis, Elisabeth Argentzell, Ulrika Bejerholm, Mona Eklund, David Brunt   +6 more
doaj   +1 more source

Madness decolonized?: Madness as transnational identity in Gail Hornstein’s Agnes’s Jacket [PDF]

, 2018
The US psychologist Gail Hornstein’s monograph Agnes’s Jacket: A Psychologist’s Search for the Meanings of Madness (2009) is an important intervention in the identity politics of the mad movement.
A Huxley, A Komaromi, A Sinfield, A Sweeney, A Woods, A Woods, AD Smith, AJ Withers, AW Frank, B Burstow, B Burstow, B McWade, B Sapey, C Hoerl, D Ferreday, D Lacapra, EC Roxburgh, G Miller, GA Hornstein, Gavin Miller, H Lane, J Clifford, J Dillon, JH McGruder, K Jaspers, KA Appiah, KL Klein, L Beckman, L Tam, M Frisch, M McKeown, M Romme, M Romme, P Beresford, P Beresford, R Brubaker, R Cohen, R Gorman, R Jenkins, R Menzies, RD Laing, S Diamond, S Dufoix, S Farber, S Fernando, S High, S McCarthy-Jones, S Orbach, S Schrader, S Vertovec, T Burridge, T Minkowitz, WB Michaels   +52 more
core   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

Advanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo, Fangzhi Lou, Peiran Yang, Yu Zhang, Li Yan, Yunmei Dong, Bing Yang, Haiyang Wang, Yiyun Liu, Juncai Pu, Richard D. Cannon, Peng Xie, Ping Ji, Xin Jin   +13 more
wiley   +1 more source