Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska +14 more
wiley +1 more source
Influences of Western Cape community service doctors' choice regarding public, rural practice. [PDF]
Baytopp TJ, Lomas-Marais V, Motsohi T.
europepmc +1 more source
The Role of Problem-Based Learning in Preparing Medical Students to Work As Community Service-Oriented Primary Care Physicians: A Systematic Literature Review. [PDF]
Forbes HM, Syed MS, Flanagan OL.
europepmc +1 more source
A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Evaluation capacity building in a rural Victorian community service organisation: A formative evaluation. [PDF]
Kavanagh BE +6 more
europepmc +1 more source
Community service nurses in primary healthcare clinics: Experiences of supervision and support from professional nurses. [PDF]
Zambodla A, Williams M, Ricks E.
europepmc +1 more source
A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
Community service rehabilitation therapists' perspectives of cross-disciplinary supervision. [PDF]
Sibiya ZN, Ross AJ.
europepmc +1 more source
Responding to change in a medical student rural community service: Insights from activity theory. [PDF]
Hu CY, Nisbet G, Chang YC.
europepmc +1 more source
Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie +17 more
wiley +1 more source

