Results 11 to 20 of about 428,182 (296)

Berberine Improves Benign Prostatic Hyperplasia via Suppression of 5 Alpha Reductase and Extracellular Signal-Regulated Kinase in Vivo and in Vitro

Frontiers in Pharmacology, 2018
Benign prostate hyperplasia (BPH) is a common disease in elderly men, characterized by proliferated prostate and urinary tract symptoms. The hormonal cascade starting by the action of 5-alpha-reductase (5AR) is known to be one of the pathways responsible
Dong-Hyun Youn, Dong-Hyun Youn, Jinbong Park, Jinbong Park, Hye-Lin Kim, Yunu Jung, Yunu Jung, JongWook Kang, JongWook Kang, Seona Lim, Seona Lim, Gahee Song, Gahee Song, Hyun Jeong Kwak, Jae-Young Um, Jae-Young Um   +15 more
doaj   +1 more source

Anxiety and clinical outcomes of patients with acute coronary syndrome: a meta-analysis

BMJ Open, 2020
Objectives Anxiety has been suggested to be associated with poor outcomes in patients with acute coronary syndrome (ACS). However, results of previous follow-up studies were inconsistent.
Jie Li, Chuanjun Zhuo, Feng Ji, Junxian Song, Xiangyang Gao, Deguo Jiang, Guangdong Chen, Suling Chen, Xiaodong Lin   +8 more
doaj   +1 more source

Brain features of nearly drug‐naïve female monozygotic twins with first‐episode schizophrenia and the classification accuracy of brain feature patterns: A pilot study

Brain and Behavior, 2021
Background Data on differences in brain features between monozygotic (MZ) twins with and without schizophrenia are scarce. Methods We compared brain features of female MZ twins with and without first‐episode schizophrenia and healthy controls (n = 20 ...
Tao Zhang, Jie Song, Ce Chen, Ran Li, Yachen Li, Yun Sun, Tao Fang, Weiwei Xu, Hongjun Tian, Chuanjun Zhuo   +9 more
doaj   +1 more source

Clustering of comorbidities [PDF]

Future Healthcare Journal, 2021
Within the last decade, clustering of comorbidities has become an increasing health problem on a global scale and will continue to challenge healthcare professionals in the coming years. People with multiple diseases find difficulties in managing their daily lives due to the implications each disease brings; attending and keeping up to date with ...
Chudasama, YV, Khunti, K, Davies, MJ
openaire   +3 more sources

Taeumjowi-tang, a Traditional Korean Sasang Remedy, Improves Obesity-Atopic Dermatitis Comorbidity by Regulating Hypoxia-Inducible Factor 1 Alpha

Frontiers in Pharmacology, 2019
Atopic dermatitis (AD) is an inflammatory disease of the skin, resulting from an immune dysfunction, that often occurs as a comorbidity of obesity. This investigation evaluated the capacity of Taeumjowi-tang (TJT), a Korean herbal formulation from the ...
Jinbong Park, Jinbong Park, Dong-Hyun Youn, Dong-Hyun Youn, JongWook Kang, Kwang Seok Ahn, Hyun Jeong Kwak, Jae-Young Um, Jae-Young Um   +8 more
doaj   +1 more source

Farnesol Has an Anti-obesity Effect in High-Fat Diet-Induced Obese Mice and Induces the Development of Beige Adipocytes in Human Adipose Tissue Derived-Mesenchymal Stem Cells

Frontiers in Pharmacology, 2017
Brown adipocytes dissipate energy as heat and hence have an important therapeutic capacity for obesity. Development of brown-like adipocytes (also called beige) is also another attractive target for obesity treatment.
Hye-Lin Kim, Yunu Jung, Yunu Jung, Jinbong Park, Dong-Hyun Youn, Dong-Hyun Youn, JongWook Kang, JongWook Kang, Seona Lim, Beom Su Lee, Mi-Young Jeong, Seong-Kyu Choe, Raekil Park, Kwang Seok Ahn, Jae-Young Um   +14 more
doaj   +1 more source

Brain imaging features in schizophrenia with co‐occurring auditory verbal hallucinations and depressive symptoms—Implication for novel therapeutic strategies to alleviate the reciprocal deterioration

Brain and Behavior, 2021
Background Auditory verbal hallucinations (AVHs) and depressive symptoms are highly prevalent in schizophrenia, and recent progress has been made in understanding the reciprocal deterioration of both symptoms through structural and functional brain ...
Chuanjun Zhuo, Tao Fang, Ce Chen, Min Chen, Yun Sun, Xiaoyan Ma, Ranli Li, Hongjun Tian, Jing Ping   +8 more
doaj   +1 more source

Acne Comorbidities

Clinical, Cosmetic and Investigational Dermatology, 2022
Acne vulgaris is a multifactorial chronic inflammatory disorder of the pilosebaceous unit, and it represents the most common skin disease affecting about 85% of adolescents in Western populations. The prevalence of acne vulgaris in developed countries is higher than that in developing countries.Emerging data has shown some systemic diseases closely ...
Yun Wang, Mingfang Zhu, Shuhui Wu, Huie Zheng   +3 more
openaire   +4 more sources

Temporal trend of comorbidity and increasing impacts on mortality, length of stay, and hospital costs of first stroke in Tianjin, North of China

Cost Effectiveness and Resource Allocation, 2021
Background Stroke patients have a high incidence of comorbidity. Previous studies have shown that comorbidity can impact on the short-term and long-term mortality after stroke.
Ruixiao Hao, Xuemei Qi, Xiaoshuang Xia, Lin Wang, Xin Li   +4 more
doaj   +1 more source

Comorbidities of COPD [PDF]

European Respiratory Review, 2013
By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality. Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco smoking is a common risk factor for many comorbidities, including coronary heart disease, heart failure and lung cancer.
Cavaillès, Arnaud, Brinchault-Rabin, Graziella, Dixmier, Adrien, Goupil, François, Gut-Gobert, Christophe, Marchand-Adam, Sylvain, Meurice, Jean-Claude, Morel, Hugues, Person-Tacnet, Christine, Leroyer, Christophe, Diot, Patrice   +10 more
openaire   +5 more sources