Results 41 to 50 of about 534,728 (260)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Prediction of in-hospital mortality of patients with SARS-CoV-2 infection by comorbidity indexes: an Italian internal medicine single center study

, 2020
Objective: Clinical outcomes in patients hospitalized for severe acute respiratory syndrome due to coronavirus (SARS-CoV-2) infection seems to be closely related with burden of comorbidities.
Di Simone E, Passaro A, OUTcome and COMorbidity Evaluation of INTernal MEDicine COVID19 (OUTCOME-INTMED-COV19) Study Collaborators., Manfredini R, Greco S, Fabbian F, Zuliani G, De Giorgio R, De Giorgi A   +8 more
core   +1 more source

The challenge of comorbidity in clinical trials for multiple sclerosis [PDF]

, 2016
Objective: We aimed to provide recommendations for addressing comorbidity in clinical trial design and conduct in multiple sclerosis (MS). Methods: We held an international workshop, informed by a systematic review of the incidence and prevalence of ...
Sormani, Maria Pia, Trojano, M, TROIANO, Maria, Miller, A, Marrie, Ruth Ann, Miller, Aaron, Thompson, A, Thompson, Alan, O'Connor, Paul, Marrie, RA, Waubant, Emmanuelle, Trojano, Maria, Reingold, Stephen, O'Connor, P, Waubant, E, Sormani, MP, O'Connor, Paul, Cohen, Jeffrey A., Reingold, S, Cohen, JA, Thompson A, attendees of the International Workshop on Comorbidity in Multiple Sclerosis, O'Connor P, Trojano M, Cohen JA, Marrie RA, Sormani MP, Miller A, Waubant E, Reingold S, COMI , GIANCARLO   +30 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

The relationship between fat distribution in central region and comorbidities in obese people: Based on NHANES 2011–2018

Frontiers in Endocrinology, 2023
BackgroundCentral obesity is closely related to comorbidity, while the relationship between fat accumulation pattern and abnormal distribution in different parts of the central region of obese people and comorbidity is not clear.
Chen-An Liu, Chen-An Liu, Chen-An Liu, Chen-An Liu, Chen-An Liu, Tong Liu, Tong Liu, Tong Liu, Tong Liu, Tong Liu, Guo-Tian Ruan, Guo-Tian Ruan, Guo-Tian Ruan, Guo-Tian Ruan, Guo-Tian Ruan, Yi-Zhong Ge, Yi-Zhong Ge, Yi-Zhong Ge, Yi-Zhong Ge, Yi-Zhong Ge, Meng-Meng Song, Meng-Meng Song, Meng-Meng Song, Meng-Meng Song, Meng-Meng Song, Hai-Lun Xie, Hai-Lun Xie, Hai-Lun Xie, Hai-Lun Xie, Hai-Lun Xie, Shi-Qi Lin, Shi-Qi Lin, Shi-Qi Lin, Shi-Qi Lin, Shi-Qi Lin, Li Deng, Li Deng, Li Deng, Li Deng, Li Deng, He-Yang Zhang, He-Yang Zhang, He-Yang Zhang, He-Yang Zhang, He-Yang Zhang, Qi Zhang, Qi Zhang, Han-Ping Shi, Han-Ping Shi, Han-Ping Shi, Han-Ping Shi, Han-Ping Shi   +51 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Predictive Risk Modelling of Hospital Emergency Readmission, and Temporal Comorbidity Index Modelling Using Machine Learning Methods [PDF]

, 2017
This thesis considers applications of machine learning techniques in hospital emergency readmission and comorbidity risk problems, using healthcare administrative data. The aim is to introduce generic and robust solution approaches that can be applied to
Mesgarpour, M.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Comorbidity in posttraumatic stress disorder: a structural equation modelling approach [PDF]

, 2008
OBJECTIVE: Posttraumatic stress disorder (PTSD) is associated with high rates of psychiatric comorbidity. Existing theories consider comorbidity as a consequence of PTSD (model 1), PTSD and comorbidity as a consequence of shared factors of vulnerability (
Wittmann, L, Wittmann, Lutz, Martin-Soelch, C, Znoj, Hansjoerg, Schnyder, U, Znoj, H, Moergeli, Hanspeter, Moergeli, H, Martin-Soelch, Chantal, Schnyder, Ulrich, Znoj, Hans Jörg   +10 more
core   +1 more source

Linking alcohol-involved sexual assault to negative emotional outcomes: the relative mediating roles of shame, self-compassion, fear of self-compassion, and self-blame

Frontiers in Psychology
IntroductionAlcohol-involved sexual assault (AISA) survivors who were drinking at the time of the assault may be at risk of internalizing victim-blaming myths and stigma.
Sherry H. Stewart, Sherry H. Stewart, Noelle Strickland, Raquel Noguiera-Arjona, Christine Wekerle   +4 more
doaj   +1 more source