Results 261 to 270 of about 765,292 (350)

Epidemiology and clinical characteristics of headache comorbidity with epilepsy in children and adolescents

, 2007
Young Il Rho
openalex   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Impact of Comorbidity Clusters on Quality of Life in Chronic Heart Failure. [PDF]

Vasc Health Risk Manag
Zhang L, Wang Y, Yuan N, Zhang Y, Yan J, Zhang L, Xiong W, Ma S, Zhang Y, Tian J.   +9 more
europepmc   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Associations of age, comorbidities, and inflammatory markers with disease severity in pediatric human metapneumovirus infection. [PDF]

Eur J Pediatr
Erdoğan KN, Gençeli M, Babayiğit E, Şimşek A, Üstüntaş T, Metin Akcan Ö, Ercan F, Gençeli S, Yücel M, Akkuş A, Pekcan S.   +10 more
europepmc   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Detecting cancer recurrence in general practice: a Danish national cohort study. [PDF]

Br J Gen Pract
Grooss K, Rasmussen LA, Christensen KS, Pedersen AF, Nekhlyudov L, Falborg AZ, Vedsted P.   +6 more
europepmc   +1 more source

1H NMR Based Serum Metabolic Profiling Reveals Differentiating Biomarkers in Patients with Diabetes and Diabetes Comorbidity

, 2018
Atul Rawat, Gunjan Misra, Madhukar Saxena, Sukanya Tripathi, Durgesh Dubey, Sulekha Saxena, Avinash Aggarwal, Varsha Gupta, M Y Khan, Anand Prakash   +9 more
openalex   +2 more sources

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

Advanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman, Lars Lau Raket, Michael Schöll, for the Alzheimer's Disease Neuroimaging Initiative†   +3 more
wiley   +1 more source

The role of comorbidity and frailty in shaping the burden of atrial fibrillation: a multinational cross-sectional survey. [PDF]

Sci Rep
Ravelli A, Trevisan C, Rivera-Caravaca JM, Zanforlini BM, Bosio C, Graffigna G, Sergi G, Dan GA, Dan AR, Roldán V, Ortuno FM, Johnsen SP, Petrovic M, Vetrano DL, Leo DG, Lane DA, AFFIRMO Consortium.   +16 more
europepmc   +1 more source