Results 281 to 290 of about 1,146,409 (382)

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

Implementation of guideline-recommended organ-protective therapy in people with type 2 diabetes and cardiovascular disease, heart failure, or kidney disease: real-world evidence from a German University Hospital. [PDF]

Front Endocrinol (Lausanne)
Suliman K, Lee-Barkey YH, Brehmer A, Stratmann B, Klose JM, Lenfers T, Kleesiek J, Reger-Tan S, Keyl J.   +8 more
europepmc   +1 more source

Psychiatric Comorbidity May Affect the Quality of Life in Pediatric Migraine Patients, Independently of Pain Frequency and Pedmidas Score

Canan Üstün, Şebnem Azime Soysal Acar, Cengiz Havalı, Zeynep Öztürk, Ebru Arhan, Kıvılcım Gücüyener, Ercan Demir   +6 more
openalex   +1 more source

Contribution of neuromuscular Impairment to physical functional Status in Patients with Lumbar Spinal Stenosis [PDF]

, 1994
Fossel, Anne H., Katz, Jeffrey N., Liang, Matthew H., Lipson, Stephen J., Stucki, Gerold   +4 more
core  

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Health-Related Quality of Life in Patients End-Stage Kidney Disease with Hypertension: Hemodialysis Vs Continuous Ambulatory Peritoneal Dialysis Using EQ-5D-5L at a Tertiary Center in Indonesia. [PDF]

Int J Nephrol Renovasc Dis
Wulandari W, Alfaqeeh M, Zakiyah N, Purba FD, Rahayu C, Shafie AA, Endarti D, Suwantika AA.   +7 more
europepmc   +1 more source

Psychedelic Research for Alcohol Use Disorder with Comorbid Major Depressive Disorder: An Unmet Need [PDF]

Daan de Jonge, Pim B. van der Meer, Cornelis Kramers, Arnt Schellekens   +3 more
openalex   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

Exploring the Animal Models of Gastrointestinal and Emotional Comorbidity. [PDF]

Brain Behav
Wang YH, Kong XR, Ye XZ, Pu S, Ren XX, Huang QY, Lu YQ, Wang H.   +7 more
europepmc   +1 more source

Evaluation of comorbidities in idiopathic pulmonary fibrosis patients

Ibrahim M. Shalan, Hytham Abdallah Abdelmaksoud, Hossam A. Mohammed, Nourelhoda G. Mahmoud   +3 more
openalex   +1 more source