Results 41 to 50 of about 388,394 (322)

The risk of comorbidity [PDF]

Annals of the Rheumatic Diseases, 2012
The field of rheumatology has shown great interest in comorbidity-related risk among patients with rheumatoid arthritis (RA). A recent paper reported that a person with RA has a similar risk of sustaining a myocardial infarction as a person with diabetes mellitus (DM), and this risk is comparable to that of a healthy person 10 years older.1 Several ...
Mark S. Lachs, Stephen A. Paget, Mary E. Charlson, Janey C. Peterson, M C Reid   +4 more
openaire   +3 more sources

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Improving Disease Comorbidity Prediction Based on Human Interactome with Biologically Supervised Graph Embedding [PDF]

International Conference on Computational Advances in Bio and Medical Sciences (ICCABS 2023). Lecture Notes in Computer Science, vol 14548
Comorbidity carries significant implications for disease understanding and management. The genetic causes for comorbidity often trace back to mutations occurred either in the same gene associated with two diseases or in different genes associated with different diseases respectively but coming into connection via protein-protein interactions. Therefore,
arxiv   +1 more source

Tools for the Assessment of Comorbidity Burden in Rheumatoid Arthritis

Frontiers in Medicine, 2018
IntroductionComorbidities influence the prognosis, clinical outcomes, disease activity, and treatment response in rheumatoid arthritis (RA). RA patients have a high-comorbidity burden necessitating their study.
Fawad Aslam, Nasim Ahmed Khan
doaj   +1 more source

Clinical Utility Gains from Incorporating Comorbidity and Geographic Location Information into Risk Estimation Equations for Atherosclerotic Cardiovascular Disease [PDF]

arXiv, 2022
Objective: There are several efforts to re-learn the 2013 ACC/AHA pooled cohort equations (PCE) for patients with specific comorbidities and geographic locations. With over 363 customized risk models in the literature, we aim to evaluate such revised models to determine if the performance improvements translate to gains in clinical utility.
arxiv  

Medical comorbidity in in-patients with psychiatric disorder

Muller Journal of Medical Sciences and Research, 2013
Objective: To study the prevalence of concurrent medical comorbidity in patients admitted with psychiatric disorders. Materials and Methods: One hundred patients with psychiatric disorders admitted to the general wards of the Department of Psychiatry ...
Christy Maria Manuel, Pavithra P Rao, Preethi Rebello, A T Safeekh, P John Mathai   +4 more
doaj   +1 more source

Linking alcohol-involved sexual assault to negative emotional outcomes: the relative mediating roles of shame, self-compassion, fear of self-compassion, and self-blame

Frontiers in Psychology
IntroductionAlcohol-involved sexual assault (AISA) survivors who were drinking at the time of the assault may be at risk of internalizing victim-blaming myths and stigma.
Sherry H. Stewart, Sherry H. Stewart, Noelle Strickland, Raquel Noguiera-Arjona, Christine Wekerle   +4 more
doaj   +1 more source

Is gain in health-related quality of life after a total hip arthroplasty depended on the comorbidity burden?

Acta Orthopaedica, 2018
Background and purpose — Using patient-reported health-related quality of life (HRQoL), approximately 10% of patients report some degree of dissatisfaction after a total hip arthroplasty (THA).
Eva N Glassou, Alma B Pedersen, Peter K Aalund, Sebastian B Mosegaard, Torben B Hansen   +4 more
doaj   +1 more source

Liraglutide for idiopathic intracranial hypertension: a real‐world propensity score‐matched study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Idiopathic intracranial hypertension (IIH) is a neurological disorder predominantly affecting young women with obesity, characterized by elevated intracranial pressure. While current treatments include weight loss counseling, medical therapies, and surgical interventions, their limitations necessitate exploring novel therapeutic ...
Ahmed Y. Azzam, Muhammed Amir Essibayi, Dhrumil Vaishnav, Mohammed A. Azab, Mahmoud M. Morsy, Osman Elamin, Adam Elswedy, Oday Atallah, Hana J. Abukhadijah, Adam A. Dmytriw, Amanda Baker, Deepak Khatri, Neil Haranhalli, David J. Altschul   +13 more
wiley   +1 more source

Clinical impact and safety of brain biopsy in unexplained central nervous system disorders: a real‐world cohort study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective A substantial part of central nervous system (CNS) disorders remains unexplained, despite various new and minimally invasive diagnostic techniques. Within this rapidly developing diagnostic field, the precise role of brain biopsy is unknown.
Robin W. van Steenhoven, Saan Salih, Juna M. de Vries, Ide Smets, Rob M. Verdijk, Mayke Gardeniers, Jeroen Kerstens, Juliette Brenner, Yvette S. Crijnen, Marjolein Geurts, Jacoline E. C. Bromberg, Corine H. GeurtsvanKessel, Peter A. E. Sillevis Smitt, Rutger K. Balvers, Maarten J. Titulaer   +14 more
wiley   +1 more source