Results 51 to 60 of about 334,818 (268)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Astrophysical Journal Letters, 2023 Climate modeling has shown that tidally influenced terrestrial exoplanets, particularly those orbiting M-dwarfs, have unique atmospheric dynamics and surface conditions that may enhance their likelihood to host viable habitats.
Howard Chen +3 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Transformation of Irregular Solid Spherical Harmonics at Parallel Translation of the Coordinate System [PDF]
Учёные записки Казанского университета: Серия Физико-математические науки, 2017 When studying physical phenomena in spatial regions bounded by spherical or slightly non-spherical surfaces, spherical functions and solid spherical harmonics are widely used.
A.A. Aganin, A.I. Davletshin
doaj
Locally Conformally Symplectic Structures on Compact Non-Kähler Complex Surfaces [PDF]
International Mathematics Research Notices, 2015 typos and a sign error in Convention 2.1 ...
Apostolov, Vestislav, Dloussky, Georges
openaire +3 more sources
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Learning developmental mode dynamics from single-cell trajectories
eLife, 2021 Embryogenesis is a multiscale process during which developmental symmetry breaking transitions give rise to complex multicellular organisms. Recent advances in high-resolution live-cell microscopy provide unprecedented insights into the collective cell ...
Nicolas Romeo +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Compact freeform near-eye display system design enabled by optical-digital joint optimization
Frontiers in PhysicsThe near-eye display (NED) systems, designed to project content into the human eye, are pivotal in the realms of augmented reality (AR) and virtual reality (VR), offering users immersive experiences.
Huiming Xu +3 more
doaj +1 more source