Results 51 to 60 of about 6,516,130 (318)
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
When is an ultracomplete space almost locally compact?
Applied General Topology, 2006 We study spaces X which have a countable outer base in βX; they are called ultracomplete in the most recent terminology. Ultracompleteness implies Cech-completeness and is implied by almost local compactness (≡having all points of non-local compactness ...
Daniel Jardón Arcos +1 more
doaj +1 more source
Inverse design and demonstration of a compact and broadband on-chip wavelength demultiplexer [PDF]
Nature Photonics, 2015 An on-chip integrated wavelength demultiplexer designed using an inverse computational algorithm is experimentally demonstrated. 1,300 and 1,550 nm wavelength light is sorted in a device area of just 2.8 × 2.8 μm2.
Alexander Piggott +5 more
semanticscholar +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
FEBS Open Bio, EarlyView.A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Wasit Journal for Pure SciencesThe object of this work to introduce a new form of fuzzy compact space in a fuzzy topological space, named by fuzzy feebly compact space. It is stronger than a fuzzy compact space.
Saad Mahdi Jaber
doaj +1 more source
Proper actions and proper invariant metrics
, 2008 We show that if a (locally compact) group $G$ acts properly on a locally compact $\sigma$-compact space $X$ then there is a family of $G$-invariant proper continuous finite-valued pseudometrics which induces the topology of $X$.
Abels, Herbert +2 more
core +2 more sources
Some topological invariants and biorthogonal systems in Banach spaces [PDF]
, 2011 We consider topological invariants on compact spaces related to the sizes of discrete subspaces (spread), densities of subspaces, Lindelof degree of subspaces, irredundant families of clopen sets and others and look at the following associations between ...
Koszmider, Piotr
core
Recognizing nullhomotopic maps into the classifying space of a Kac-Moody group
, 2015 This paper extends certain characterizations of nullhomotopic maps between p-compact groups to maps with target the p-completed classifying space of a connected Kac-Moody group and source the classifying space of either a p-compact group or a connected ...
Foley, John D.
core +1 more source
Compact folded metasurface spectrometer [PDF]
Nature Communications, 2018 An optical design space that can highly benefit from the recent developments in metasurfaces is the folded optics architecture where light is confined between reflective surfaces, and the wavefront is controlled at the reflective interfaces.
Mohammadsadegh Faraji-Dana +5 more
semanticscholar +1 more source