Results 61 to 70 of about 6,651,322 (372)

Recognizing nullhomotopic maps into the classifying space of a Kac-Moody group

open access: yes, 2015
This paper extends certain characterizations of nullhomotopic maps between p-compact groups to maps with target the p-completed classifying space of a connected Kac-Moody group and source the classifying space of either a p-compact group or a connected ...
Foley, John D.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

When is an ultracomplete space almost locally compact?

open access: yesApplied General Topology, 2006
We study spaces X which have a countable outer base in βX; they are called ultracomplete in the most recent terminology. Ultracompleteness implies Cech-completeness and is implied by almost local compactness (≡having all points of non-local compactness ...
Daniel Jardón Arcos   +1 more
doaj   +1 more source

Inverse design and demonstration of a compact and broadband on-chip wavelength demultiplexer [PDF]

open access: yesNature Photonics, 2015
An on-chip integrated wavelength demultiplexer designed using an inverse computational algorithm is experimentally demonstrated. 1,300 and 1,550 nm wavelength light is sorted in a device area of just 2.8 × 2.8 μm2.
Alexander Piggott   +5 more
semanticscholar   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

On Fuzzy Feebly Compact Space

open access: yesWasit Journal for Pure Sciences
The object of this work to introduce a new form of fuzzy compact space in  a fuzzy topological space, named by fuzzy feebly compact space. It is stronger than a fuzzy compact space.
Saad Mahdi Jaber
doaj   +1 more source

On Harmonic Hilbert Spaces on Compact Abelian Groups [PDF]

open access: hybrid, 2023
Suddhasattwa Das, Dimitrios Giannakis
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Some topological invariants and biorthogonal systems in Banach spaces [PDF]

open access: yes, 2011
We consider topological invariants on compact spaces related to the sizes of discrete subspaces (spread), densities of subspaces, Lindelof degree of subspaces, irredundant families of clopen sets and others and look at the following associations between ...
Koszmider, Piotr
core  

Compact directed spaces [PDF]

open access: yesTransactions of the American Mathematical Society, 1970
A directed space is a partially ordered topological space in which each two elements have a common predecessor. It is a consequence of a theorem of A. D. Wallace that a compact directed space is acyclic if each of its principal ideals is acyclic. This result is extended by considering the situation where at most finitely many principal ideals are not ...
openaire   +2 more sources

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