Results 91 to 100 of about 167,675 (289)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Compact orthoalgebras [PDF]

open access: yesProceedings of the American Mathematical Society, 2005
We initiate a study of topological orthoalgebras (TOAs), concentrating on the compact case. Examples of TOAs include topological orthomodular lattices, and also the projection lattice of a Hilbert space. As the latter example illustrates, a lattice-ordered TOA need not be a topological lattice.
openaire   +3 more sources

Soil compaction

open access: yes, 2018
Project relevance: For construction of roads and embankments, soil material must be compacted to its densest state, which will result in higher soil strength and long-term stability.
Dong-Sheng Jeng   +5 more
core   +1 more source

The Effect of Varying Compaction Levels on Soil Dynamic Properties and the Growth of Canola (Brassica napus L.)

open access: yesAgriculture
Extremely low field emergence rates for canola are primarily attributed to soil compaction from field traffic during and after planting. This study aimed to determine the critical compaction level for canola emergence across different soil types.
Ernest Owusu-Sekyere, Ying Chen
doaj   +1 more source

Oral Modified Release Multiple-Unit Particulate Systems: Compressed Pellets, Microparticles and Nanoparticles

open access: yesPharmaceutics, 2018
Oral modified-release multiparticulate dosage forms, which are also referred to as oral multiple-unit particulate systems, are becoming increasingly popular for oral drug delivery applications.
Nihad Al-Hashimi   +4 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Particle Sedimentation in a Fluid at Low Reynolds Number: A Generalization of Hindered Settling Described by a Two‐Phase Continuum Model

open access: yesGeochemistry, Geophysics, Geosystems
Particle‐fluid separation by settling is a ubiquitous process in Earth and Planetary Sciences. The settling velocity of particles is controlled by a balance between buoyancy and drag forces.
C. Huber, E. M. Parmentier, D. Florez
doaj   +1 more source

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