Results 101 to 110 of about 59,612 (299)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Circulating tumour cell PD-L1 test for head and neck cancers
, 2017 Immune checkpoint inhibitors have gained traction over the last few years in the treatment of metastatic/recurrent head and neck squamous cell carcinoma (HNSCC) patients.
Chamindie Punyadeera +5 more
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Analysis of companion cell and phloem metabolism using a transcriptome-guided model of Arabidopsis metabolism. [PDF]
Plant Physiol, 2023 Hunt H +7 more
europepmc +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The companion dog as a unique translational model for aging
, 2017 The dog is a unique species due to its wide variation among breeds in terms of size, morphology, behaviour and lifespan, coupled with a genetic structure that facilitates the dissection of the genetic architecture that controls these traits.
Augusto Carluccio +9 more
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Can friends be copied?:Ethical aspects of cloning dogs as companion animals [PDF]
, 2018 Since the first successful attempt to clone a dog in 2005, dogs have been cloned by Somatic Cell Nuclear Transfer (SCNT) for a variety of purposes. One of these is to clone dogs as companion animals.
Gjerris, Mickey +7 more
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AnimalsEnsuring the safety of mesenchymal stem cell (MSC) therapy is a fundamental requirement in clinical practice. This study aimed to assess the safety of using gonadal tissue-derived MSCs (n = 10) compared to the commonly utilized adipose tissue-derived ...
So-Young Jeung +3 more
doaj +1 more source
Efficacy of the porcine species in biomedical research
Frontiers in Genetics, 2015 Since domestication, pigs have been used extensively in agriculture and kept as companion animals. More recently they have been used in biomedical research, given they share many physiological and anatomical similarities with humans. Recent technological
Karina eGutierrez +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Natural killer cell evolution: cellular and molecular studies on Xenopus [PDF]
, 1996 The presence of natural killer cells at lower evolutionary levels was investigated in the amphibian Xenopus laevis. Chromium release microcytotoxicity assays revealed that fresh splenocytes from early-thymectomised Xenopus displayed significant ...
Horsham, Karen
core