Results 201 to 210 of about 56,758 (258)

Tracking spread of carbapenemase-producing Enterobacterales between humans and companion animals: successes and challenges. [PDF]

Front Cell Infect Microbiol
Dietrich JM, Vagnone PMS, Dale JL, Beaudoin AL, Ruhland A, Kollmann L, Cole SD.   +6 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A digital twin approach for transforming prescription drug labeling. [PDF]

Front Pharmacol
Kimko H, Kimko E, Venkatapurapu SP.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Case Report: Transferable IncX4 plasmid carrying <i>mcr-1</i> in colistin-resistant <i>Escherichia coli</i> from a healthy pet dog in South Korea. [PDF]

Front Vet Sci
Oh JY, Kwak SM, Kim JY, Ro WB, Lee KJ, Chae JC.   +5 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Raman signatures of <i>Cnm</i>-positive <i>Streptococcus mutans</i>: II, screening the virulence of clinical isolates. [PDF]

Front Microbiol
Pezzotti G, Adachi T, Kitagawa K, Ikegami S, Imamura H, Yamamoto T, Okuma K, Matsuo Y, Zhu W, Yasukochi Y, Higasa K, Nishihama S, Takeda K, Shiba H, Kawada-Matsuo M, Komatsuzawa H.   +15 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Antimicrobial resistance and genetic characterization of <i>Clostridium perfringens</i> isolated from companion animals in South Korea, 2018-2024. [PDF]

One Health
Choi JH, Ali MS, Lee YH, Kang HS, Park SC, Moon BY, Lim SK.   +6 more
europepmc   +1 more source