Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
DNA and RNA-based next-generation sequencing for companion diagnostic rearrangement detection in solid tumors. [PDF]
OncologistKeller-Evans RB +7 more
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
TIP-20, a novel feline McDonough sarcoma-like tyrosine kinase 3 inhibitor with potent antileukemia activity. [PDF]
J Int Med ResPang H +8 more
europepmc +1 more source
The missing link: electronic health record linkage across species offers opportunities for improving One Health. [PDF]
JAMIA OpenMullen KR +9 more
europepmc +1 more source
Divergent Embryo Responses to Chemical Cues in Two Freshwater Fishes with Different Parental Care Strategies. [PDF]
Animals (Basel)Zhang N +7 more
europepmc +1 more source
Dogs and humans share biomarkers of mortality. [PDF]
J Gerontol A Biol Sci Med SciHarrison BR +6 more
europepmc +1 more source
Correction to "Utility of a Novel High-Sensitivity Multiplex Companion Diagnostic Test Using Formalin-Fixed Paraffin-Embedded Cell Block Materials of Non-Small Cell Lung Cancer". [PDF]
Cancer Medeuropepmc +1 more source