Results 51 to 60 of about 2,508,939 (306)

Investment Characteristics of Natural Monopoly Companies [PDF]

open access: yesJournal of Competitiveness, 2012
This paper explores the possibilities of investment by private investors in natural monopoly companies. The paper analyzes the broad issue of risk measurement with focus on downside risk measurement principle. The main scientific aim is to adopt a more sophisticated and theoretically advanced statistical technique and apply them to the findings.
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Weather Regimes of Extreme Wind Speed Events in Xinjiang: A 10–30 Year Return Period Analysis

open access: yesAtmosphere
Xinjiang is a critical wind energy region in China. This study characterizes extreme wind speed (EWS) events in Xinjiang by using ERA5 reanalysis (1979–2023) and station observations (2022–2023).
Yajie Li   +7 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Typology of logging companies in the Brazilian Amazon [PDF]

open access: yes, 2011
After 20 years of labeling with a strong increase of certified surfaces all around the world, real advantages and inconveniences of a company certified with regard to a normal company are not well known.
Martinez Plaza, Santiago   +2 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Dividend Omission Announcement Effect to Market Reaction in Indonesia Stock Exchange

open access: yesIntegrated Journal of Business and Economics, 2018
This study examined the signalling theory about how the market / investors respond to dividend announcements made by companies listed on the Indonesia Stock Exchange during the period 2008-2012.
Mr Darmawan
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Effect of Company Characteristics and Corporate Governance on the Practices of Intellectual Capital Disclosure

open access: yesInternational Research Journal of Business Studies, 2018
This study aimed to reveal the effect of company characteristics, company size i.e., profitability, leverage, liquidity, and industry type; and corporate governance structure, consisting of the audit firm size and the independent commissioners ...
Isnalita, Fitri Romadhon
doaj   +1 more source

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