Results 241 to 250 of about 2,675,281 (341)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Research Communication: Effects of Screening Colonoscopy on Colorectal Cancer Mortality: Lessons From Comparative Analyses of Randomised Trials. [PDF]

Aliment Pharmacol Ther
Brenner H, Sergeev D, Heisser T, Hoffmeister M.   +3 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The complete mitochondrial genomes of the two species of Astyanax (Characiformes: Acestrorhamphidae) that occur in cenotes of the Yucatán Peninsula karst aquifer: comparative analyses and their taxonomic implications. [PDF]

Mol Biol Rep
Arroyave J, Mar-Silva AF, Badillo-Alemán M, Ochoa-Zavala M.   +3 more
europepmc   +1 more source

Comparative analyses for the audiological outcomes between CI subjects with less than 7 vs. more than 7 semitonal mismatches.

Nezar Hamed (22537844), Asma Alahmadi (20234511), Isra Aljazeeri (22537847), Yassin Abdelsamad (18794348), Hanaa Alotaibi (22537850), Abdulrahman Hagr (18794351), Medhat Yousef (22537853)   +6 more
openalex   +1 more source

Genome-Wide Polymorphism and Comparative Analyses in the White-Tailed Deer (Odocoileus virginianus): A Model for Conservation Genomics

, 2011
Christopher M. Seabury, Eric K. Bhattarai, Jeremy F. Taylor, Ganesh Viswanathan, Susan M. Cooper, Donald S. Davis, Scot E. Dowd, Mitch L. Lockwood, Paul Seabury   +8 more
openalex   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Comparative Analyses of Four Reference Genomes Reveal Exceptional Diversity and Weak Linked Selection in the Yellow Monkeyflower (Mimulus guttatus) Complex. [PDF]

Mol Ecol Resour
Lovell JT, Walstead R, Lawrence A, Stark-Dykema E, Farnitano MC, Harder A, Brůna T, Barry K, Goodstein D, Jenkins J, Lipzen A, Boston L, Webber J, Chovatia M, Eichenberger J, Talag J, Grimwood J, Schmutz J, Kelly JK, Sweigart AL, Fishman L, Willis JH.   +21 more
europepmc   +1 more source

Supplementary Table S5 from Pan-Cancer Comparative and Integrative Analyses of Driver Alterations Using Japanese and International Genomic Databases

Sara Horie, Yuki Saito, Yasunori Kogure, Kota Mizuno, Yuta Ito, Mariko Tabata, Takanori Kanai∥, Koichi Murakami, Junji Koya, Keisuke Kataoka   +9 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source