Results 281 to 290 of about 2,675,281 (341)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Comparative Analyses of Van Nuys Prognostic Index and NCCN Guidelines in Ductal Carcinoma <i>In Situ</i> Treatment in a Brazilian Hospital. [PDF]

Life (Basel)
Antonini M, Barros Vasconcelos R, Mattar A, Medeiros MP, Teixeira MD, Amorim AG, Ferraro O, de Oliveira LC, Ramos MDNM, Cavalcante FP, Zerwes F, Madeira M, Millen EC, Frasson AL, Brenelli FP, Facina G, Couto HL, Gebrim LH.   +17 more
europepmc   +1 more source

A male-specific insert of Opsariichthys bidens identified based on genome-wide association analyses and comparative genomics

Xiaojun Xu, Jiongying Yu, Jianhui Ge, Shaokui Yi, Xudong Weng, Wenzhi Guan, Baolong Niu, Xinhui Zhang, Bao Lou   +8 more
openalex   +1 more source

Comparative Analyses of the Safety Profiles of Vitamin D Receptor Agonists: A Pharmacovigilance Study Based on the EudraVigilance Database. [PDF]

Pharmaceuticals (Basel)
Gáll Z, Kolcsar M.
europepmc   +1 more source

Comparative analyses of persistence traits in Escherichia coli O157:H7 strains belonging to different clades including REPEXH01 and REPEXH02 strains. [PDF]

Front Microbiol
Carter MQ, Carychao D, Bono JL.
europepmc   +1 more source

Comparative Analyses Reveal Conserved and Modified Steps in the Testis Descent and Scrotum Development in Mouse and Opossum.

Cells Tissues Organs
Wakamatsu Y, Takeda Y, Tamura K, Suzuki K, Kiyonari H, Yamada G.   +5 more
europepmc   +1 more source

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International Journal of Procedural Law, 2021
On 18 March 1970, the Hague Convention on the Taking of Evidence Abroad in Civil or Commercial Matters was concluded. On the occasion of the Convention’s Golden Anniversary, this article takes a look back on the major issues that arose in the cross- border cooperation between the Contracting States, for example the notorious orders for discovery and ...
openaire   +2 more sources