Results 51 to 60 of about 369,301 (291)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Behavioral SciencesAttachment is an emotional bond based on the first relationships formed between people. In the case of institutionalized children, it is more difficult to establish a secure attachment bond with an adult.
María-Jesús Martínez-Usarralde +3 more
doaj +1 more source
Teacher Professional Development: International Perspectives and Approaches [PDF]
Psychology, Society & Education, 2015 Nations around the world are currently embarked in deep reforms of their education systems. There is widespread agreement among policymakers, scholars, and educators that one of the keys for success during these reforms is promoting the professional ...
Alfredo Bautista, Rosario Ortega-Ruíz
doaj
Revista Española de Educación Comparada, 2014 En este artículo se presentan las diferentes redes académicas que se han creado en torno a la educación comparada y se hace hincapié en las listas de distribución, especialmente en las específicas de la Educación Comparada (Compared, AFEC-Info y Edu-Comp)
Luis M. Naya
doaj +1 more source
Enhancing Sustainable Arts Education: Comparative Analysis of Creative Process Measurement Techniques [PDF]
, 2023 Churan Wang +2 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Frontiers in EducationGlobally, there is currently no shared or decided-upon definition of middle leadership, and South Africa is no exception. This study aimed to identify and analyze empirical peer-reviewed articles on middle leadership to understand how middle leaders are ...
Michael Moreti Mahome +1 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source