Results 31 to 40 of about 6,022,305 (300)

A co-designed, community-based intensive health behavior intervention promotes participation and engagement in youth with risk factors for type 2 diabetes

Frontiers in Clinical Diabetes and Healthcare, 2023
BackgroundObesity among youth (children and adolescents) is associated with increased risk for youth-onset type 2 diabetes. Lifestyle change can delay or prevent the development of type 2 diabetes, yet real-world implementation of health behavior ...
Julie M. Pike, Julie M. Pike, Kathryn M. Haberlin-Pittz, Kathryn M. Haberlin-Pittz, Basmah S. Alharbi, Susan M. Perkins, Susan M. Perkins, Tamara S. Hannon, Tamara S. Hannon   +8 more
doaj   +1 more source

Patients’ responses to incidentally discovered silent brain infarcts – a qualitative study

Journal of Patient-Reported Outcomes, 2019
Background Incidentally discovered silent brain infarcts (id-SBIs) are an understudied condition with probable clinical significance, but it is not known how patients respond to or prioritize this condition.
Lester Y. Leung, Paul K. J. Han, Christine Lundquist, Gene Weinstein, David E. Thaler, David M. Kent   +5 more
doaj   +1 more source

Open-chest versus closed-chest cardiopulmonary resuscitation in trauma patients with signs of life upon hospital arrival: a retrospective multicenter study

Critical Care, 2020
Background The effectiveness and indications of open-chest cardiopulmonary resuscitation (OCCPR) have been still debatable. Although current guidelines state that the presence of signs of life (SOL) is an indication for OCCPR, scientific evidence ...
Akira Endo, Mitsuaki Kojima, Zhi-Jie Hong, Yasuhiro Otomo, Raul Coimbra   +4 more
doaj   +1 more source

Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression : An Update of the 2007 Comparative Effectiveness Review [Internet]

, 2011
BACKGROUND:  Depressive disorders such as major depressive disorder (MDD), dysthymia, and subsyndromal depression may be serious disabling illnesses. MDD affects more than 16 percent of adults at some point during their lifetimes.
Gartlehner, Gerald, Thaler, Kylie, Lux, Linda, Thieda, Patricia, Lloyd, Stacey, Gaynes, Bradley N, Reichenpfader, Ursula, Hansen, Richard A, Lohr, Kathleen N, Morgan, Laura C, Mager, Ursula, Strobelberger, Michaela, Van Noord, Megan   +12 more
core   +2 more sources

Field Synopsis of the Role of Sex in Stroke Prediction Models

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundGuidelines for stroke prevention recommend development of sex‐specific stroke risk scores. Incorporating sex in Clinical Prediction Models (CPMs) may support sex‐specific clinical decision making.
Jessica K. Paulus, Lana Y. H. Lai, Christine Lundquist, Ali Daneshmand, Hannah Buettner, Jennifer S. Lutz, Gowri Raman, Benjamin S. Wessler, David M. Kent   +8 more
doaj   +1 more source

Association of Incidentally Discovered Covert Cerebrovascular Disease Identified Using Natural Language Processing and Future Dementia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Covert cerebrovascular disease (CCD) has been shown to be associated with dementia in population‐based studies with magnetic resonance imaging (MRI) screening, but dementia risk associated with incidentally discovered CCD is not known. Methods
David M. Kent, Lester Y. Leung, Yichen Zhou, Patrick H. Luetmer, David F. Kallmes, Jason Nelson, Sunyang Fu, Eric J. Puttock, Chengyi Zheng, Hongfang Liu, Wansu Chen   +10 more
doaj   +1 more source

Association between cancer‐specific adverse event triggers and mortality: A validation study

Cancer Medicine, 2020
Background As there are few validated measures of patient safety in clinical oncology, creating an efficient measurement instrument would create significant value.
Saul N. Weingart, Jason Nelson, Benjamin Koethe, Omar Yaghi, Stephan Dunning, Albert Feldman, David Kent, Allison Lipitz‐Snyderman   +7 more
doaj   +1 more source

Prognostic models for COVID-19 needed updating to warrant transportability over time and space

BMC Medicine, 2022
Background Supporting decisions for patients who present to the emergency department (ED) with COVID-19 requires accurate prognostication. We aimed to evaluate prognostic models for predicting outcomes in hospitalized patients with COVID-19, in different
David van Klaveren, Theodoros P. Zanos, Jason Nelson, Todd J. Levy, Jinny G. Park, Isabel R. A. Retel Helmrich, Judith A. C. Rietjens, Melissa J. Basile, Negin Hajizadeh, Hester F. Lingsma, David M. Kent   +10 more
doaj   +1 more source

Sex Differences in Early Cardiovascular and All-Cause Hospitalization Outcomes After Surviving Firearm Injury

American Journal of Men's Health, 2018
The majority of the burden of firearm injury in the United States is on men as compared to women. There is limited evidence regarding sex differences in short-term hospitalization outcomes after surviving firearm injury.
Yi Zuo, Elizabeth C Pino, Mrithyunjay Vyliparambil, Bindu Kalesan   +3 more
doaj   +1 more source

Response to Immune Checkpoint Inhibitor Treatment in Advanced Cervical Cancer and Biomarker Study

Frontiers in Medicine, 2021
Background: Checkpoint inhibitor immunotherapy or immuno-oncology (IO) treatment in refractory cervical cancer yielded an objective response rate (ORR) of 12% in tumors expressing the programmed cell death ligand-1 (PD-L1) in the KEYNOTE-158 phase II ...
Kevin R. Shieh, Anna Huang, Yiqing Xu
doaj   +1 more source