Results 51 to 60 of about 6,022,305 (300)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Benefits and limits of comparative effectiveness studies in evidence-based conservation [PDF]

, 2019
Conservation action aims at halting the erosion of biodiversity. Assessing the outcome of a conservation intervention is thus key to improving its efficiency. This is often done by comparing an intervention to a control. Comparative effectiveness studies,
Arlettaz, Raphaël, Schaub, Michael, Schmidt, Benedikt R., Kröpfli, Madeleine, Lüscher, Beatrice   +4 more
core   +2 more sources

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Comparative Effectiveness Research and CAM [PDF]

The Journal of Alternative and Complementary Medicine, 2010
Aphrase that one hears increasingly these days in biomedical circles is “comparative effectiveness research” (CER). No doubt, part of the reason is the fact that the current administration in the United States has promised a large wave of funding for CER.
openaire   +2 more sources

Comparative effectiveness of acupuncture in sham-controlled trials for knee osteoarthritis: A systematic review and network meta-analysis

Frontiers in Medicine, 2023
ObjectivesAlthough many trials have assessed the effect of acupuncture on knee osteoarthritis (KOA), its efficacy remains controversial. Sham acupuncture techniques are regarded as representative control interventions in acupuncture trials and sometimes ...
Boram Lee, Tae-Hun Kim, Stephen Birch, Terje Alraek, Terje Alraek, Hye Won Lee, Arya Nielsen, L. Susan Wieland, Myeong Soo Lee   +8 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Sexual-orientation disparities in whole person health: age- and gender-stratified analysis of patients in a safety-net system

International Journal for Equity in Health
Introduction Despite advancements in LGB+ rights, LGB+ individuals continue to face significant healthcare disparities, particularly in areas such as homelessness, mental health, substance use, health service access, and victimization.
Dhruv Khurana, Maryah Garner, Brittany Bass, Bijan Sasininia, Geoffrey Leung, Anthony Firek   +5 more
doaj   +1 more source

Estimating individualized treatment effects from randomized controlled trials: a simulation study to compare risk-based approaches

BMC Medical Research Methodology, 2023
Background Baseline outcome risk can be an important determinant of absolute treatment benefit and has been used in guidelines for “personalizing” medical decisions.
Alexandros Rekkas, Peter R. Rijnbeek, David M. Kent, Ewout W. Steyerberg, David van Klaveren   +4 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Comparative results from included studies–effectiveness review.

, 2020
Comparative results from included studies–effectiveness review.
Kaitlyn Atkins (8293719), Julia Samuelson (3149397), Michael D. Sweat (8293728), Ping Teresa Yeh (4389484), Caitlin E. Kennedy (8293722), Rachel Baggaley (3619664), George W. Rutherford (7252592), Virginia A. Fonner (8293725), Kevin R. O’Reilly (8293731)   +8 more
core   +1 more source