Results 21 to 30 of about 74,016,645 (279)

Tufts PACE Clinical Predictive Model Registry: update 1990 through 2015

Diagnostic and Prognostic Research, 2017
Background Clinical predictive models (CPMs) estimate the probability of clinical outcomes and hold the potential to improve decision-making and individualize care.
Benjamin S. Wessler, Jessica Paulus, Christine M. Lundquist, Muhammad Ajlan, Zuhair Natto, William A. Janes, Nitin Jethmalani, Gowri Raman, Jennifer S. Lutz, David M. Kent   +9 more
doaj   +1 more source

Prehabilitation and Rehabilitation for Major Joint Replacement [PDF]

, 2021
The authors gratefully acknowledge the following individuals for their contributions to this project: Professor Emerita Carol A. Oatis, P.T., Ph.D., from Arcadia University, Glenside, PA; Associate Editor Margaret A. Maglione, B.A., M.P.P., from the RAND
KJ, Konnyu, Bhuma, Monika Reddy, Balk, Ethan M, Mehta, S, Pinto, D, Racine-Avila, J, Panagiotou, Orestis, Thoma, Louise M, Adam, Gaelen P, Aaron, Roy K, Cao, W   +10 more
core   +1 more source

Resuming elective surgical services in times of COVID-19 infection

Trauma Surgery & Acute Care Open, 2020
The consequences of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus have been devastating to the healthcare system.As the positive effects of social distancing, mandatory masking, and societal lockdown on the spread of the disease ...
Raul Coimbra, Sara Edwards, Bruno Cammarota Coimbra, Arnold Tabuenca   +3 more
doaj   +1 more source

A Clinical Model to Predict the Occurrence of Select High-risk Infections in the First Year Following Heart Transplantation

Transplantation Direct, 2023
Background. Invasive infection remains a dangerous complication of heart transplantation (HT). No objectively defined set of clinical risk factors has been established to reliably predict infection in HT.
Whitney A. Perry, MD, MS, Jennifer K. Chow, MD, MS, Jason Nelson, MPH, David M. Kent, MD, MS, David R. Snydman, MD   +4 more
doaj   +1 more source

The Methods of Comparative Effectiveness Research [PDF]

Annual Review of Public Health, 2012
This review describes methods used in comparative effectiveness research (CER). The aim of CER is to improve decisions that affect medical care at the levels of both policy and the individual. The key elements of CER are (a) head-to-head comparisons of active treatments, (b) study populations typical of day-to-day clinical practice, and (c) a focus on ...
Harold C, Sox, Steven N, Goodman
openaire   +2 more sources

Independent investigator incubator (I3): a comprehensive mentorship program to jumpstart productive research careers for junior faculty

BMC Medical Education, 2018
Background In the highly competitive environment of academic medicine, junior faculty investigators face high attrition rates due to challenges in finding effective mentorship, securing grant funding, and obtaining resources to support their career ...
John Paul Spence, Jennifer L. Buddenbaum, Paula J. Bice, Julie L. Welch, Aaron E. Carroll   +4 more
doaj   +1 more source

Performance metrics for models designed to predict treatment effect

BMC Medical Research Methodology, 2023
Background Measuring the performance of models that predict individualized treatment effect is challenging because the outcomes of two alternative treatments are inherently unobservable in one patient.
C. C. H. M. Maas, D. M. Kent, M. C. Hughes, R. Dekker, H. F. Lingsma, D. van Klaveren   +5 more
doaj   +1 more source

Predictably unequal: understanding and addressing concerns that algorithmic clinical prediction may increase health disparities

npj Digital Medicine, 2020
The machine learning community has become alert to the ways that predictive algorithms can inadvertently introduce unfairness in decision-making.
Jessica K. Paulus, David M. Kent
doaj   +1 more source

Predictive approaches to heterogeneous treatment effects: a scoping review

BMC Medical Research Methodology, 2020
Background Recent evidence suggests that there is often substantial variation in the benefits and harms across a trial population. We aimed to identify regression modeling approaches that assess heterogeneity of treatment effect within a randomized ...
Alexandros Rekkas, Jessica K. Paulus, Gowri Raman, John B. Wong, Ewout W. Steyerberg, Peter R. Rijnbeek, David M. Kent, David van Klaveren   +7 more
doaj   +1 more source

Comparative effectiveness research across two spine registries [PDF]

, 2012
Comparative effectiveness research in spine surgery is still a rarity. In this study, pain alleviation and quality of life (QoL) improvement after lumbar total disc arthroplasty (TDA) and anterior lumbar interbody fusion (ALIF) were anonymously compared ...
Diel, P., Moulin, Patrick, Henning, Julia, Henning, J., SWISSspine, and Spine Tango Registry groups, Diel, Peter, Moulin, P., Aghayev, Emin, Aghayev, E., Munting, Everard, Röder, Christoph, Munting, E., Röder, C., Munting E, Röder C, Aghayev E, Moulin P, Henning J, Diel P   +18 more
core   +2 more sources