Results 121 to 130 of about 823,177 (315)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
SensorsThis study investigates the application of hyperspectral image space–spectral fusion technology in lithologic classification, using data from China’s GF-5 and Europe’s Sentinel-2A.
Yujin Chi +5 more
doaj +1 more source
Comparative evaluation of zero deforestation governance
, 2017 This article assesses seven deforestation initiatives. The governance quality of a range of non-state zero deforestation initiatives, as assessed by stakeholder surveys, reveals a general level of satisfaction, but not overwhelming support.
Cadman, Tim +3 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Materials ProceedingsAccurate predictions of hydrate dissociation conditions are of paramount importance for optimizing mitigation strategies and preventing hydrate formation in oil and gas operations.
Ismail Ismail, Vassilis Gaganis
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Software process quality models: a comparative evaluation [PDF]
, 2003 Numerous software processes are implemented by software organisations in the production and maintenance of software products. Varying levels of success are observed in their execution, as processes vary in content and quality.
Jonathan Tate, Tate, Jonathan
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Outcomes and Causal Inference in International Comparative Assessments
, 2014 The main aim of this essay is to discuss how international large-scale assessments can be utilized for policy evaluation studies. We overview key findings from previous studies and propose the curriculum as an organizing concept in considering firstly ...
Gustafsson, Jan-Eric, +3 more
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