Results 1 to 10 of about 80,578 (289)
Amplifications of EVX2 and HOXD9-HOXD13 on 2q31 in mature cystic teratomas of the ovary identified by array comparative genomic hybridization may explain teratoma characteristics in chondrogenesis and osteogenesis [PDF]
Journal of Ovarian ResearchBackground Teratomas are a common type of germ cell tumor. However, only a few reports on their genomic constitution have been published. The study of teratomas may provide a better understanding of their stepwise differentiation processes and molecular ...
Wen-Chung Wang +3 more
doaj +2 more sources
Array Comparative Genomic Hybridization Analysis of Products of Conception in Recurrent Pregnancy Loss for specific anomalies detected by USG. [PDF]
Reprod Fertil, 2023 Gajjar K +4 more
europepmc +2 more sources
Biology, Medicine & Natural Product Chemistry, 2022 This paper aimed to understand and compare the two popular cytogenetic techniques of fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH) in detecting breast cancer chromosomal abnormality.
Harem Othman Smail
doaj +1 more source
Comparative genomic hybridization
Annual Review of Genomics and Human Genetics, 2005 ▪ Abstract Altering DNA copy number is one of the many ways that gene expression and function may be modified. Some variations are found among normal individuals ( 14 , 35 , 103 ), others occur in the course of normal processes in some species ( 33 ), and still others participate in causing various disease states.
Daniel, Pinkel, Donna G, Albertson
openaire +3 more sources
Application of array comparative genomic hybridization in Korean children under 6 years old with global developmental delay [PDF]
Korean Journal of Pediatrics, 2017 PurposeRecent advancements in molecular techniques have greatly contributed to the discovery of genetic causes of unexplained developmental delay. Here, we describe the results of array comparative genomic hybridization (CGH) and the clinical features of
Kyung Yeon Lee, Eunsim Shin
doaj +1 more source
Haematologica, 2008 Background Cytogenetic analysis of classical Hodgkin’s lymphoma is limited by the low content of the neoplastic Hodgkin-Reed-Sternberg cells in the affected tissues. However, available cytogenetic data point to an extreme karyotype complexity.
Sylvia Hartmann +14 more
doaj +1 more source
Comparative Genomic Hybridization
Archives of Pathology & Laboratory Medicine, 2001 Comparative genomic hybridization (CGH) allows a genome-wide survey of the relative copy number of tumor DNA in a single hybridization. The tumor-cell DNA (Test DNA) is hybridized together with a sex-matched normal DNA (Reference DNA) onto normal metaphase spreads.
Irene J. Barrett +5 more
openaire +3 more sources
Genomic profiling of submucosal-invasive gastric cancer by array-based comparative genomic hybridization. [PDF]
PLoS ONE, 2011 Genomic copy number aberrations (CNAs) in gastric cancer have already been extensively characterized by array comparative genomic hybridization (array CGH) analysis.
Akiko Kuroda +16 more
doaj +1 more source
Reporting Unwelcome Unanticipated Findings of Diagnostic Genomic Studies
Voices in Bioethics, 2014 The introduction of comparative genomic hybridization has revolutionized clinical genetics. It is used as a routine approach to the workup of developmental delays and multiple malformations.1-3 By subdividing chromosomes into their submicroscopic ...
Brian James Hanrahan, Robert Roger Lebel
doaj +1 more source
Journal of Biochemical and Clinical Genetics, 2018 Background: This report provides a molecular cytogenetic characterization of an Omani girl with 19p13.12 microdeletion and compares her clinical features of global developmental delay (GDD) and multiple congenital anomalies with the gene mutations and ...
Musallam Said Al-Araimi +3 more
doaj +1 more source