Results 1 to 10 of about 174,992 (335)

Amplifications of EVX2 and HOXD9-HOXD13 on 2q31 in mature cystic teratomas of the ovary identified by array comparative genomic hybridization may explain teratoma characteristics in chondrogenesis and osteogenesis [PDF]

Journal of Ovarian Research
Background Teratomas are a common type of germ cell tumor. However, only a few reports on their genomic constitution have been published. The study of teratomas may provide a better understanding of their stepwise differentiation processes and molecular ...
Wen-Chung Wang, Tai-Cheng Hou, Chen-Yun Kuo, Yen-Chein Lai   +3 more
doaj   +2 more sources

The Roles of the Fluorescent In Situ Hybridization (FISH) and Comparative Genomic Hybridization (CGH) Techniques in the Detection of the Breast Cancer

Biology, Medicine & Natural Product Chemistry, 2022
This paper aimed to understand and compare the two popular cytogenetic techniques of fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH) in detecting breast cancer chromosomal abnormality.
Harem Othman Smail
doaj   +1 more source

Microarray-based ultra-high resolution discovery of genomic deletion mutations [PDF]

, 2014
BACKGROUND: Oligonucleotide microarray-based comparative genomic hybridization (CGH) offers an attractive possible route for the rapid and cost-effective genome-wide discovery of deletion mutations.
Baban, D., Belfield, E., Brown, C., Gan, X., Harberd, N., Jiang, C., Mithani, A., Mott, R., Ragoussis, J.   +8 more
core   +5 more sources

Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin’s lymphoma by array-based comparative genomic hybridization

Haematologica, 2008
Background Cytogenetic analysis of classical Hodgkin’s lymphoma is limited by the low content of the neoplastic Hodgkin-Reed-Sternberg cells in the affected tissues. However, available cytogenetic data point to an extreme karyotype complexity.
Sylvia Hartmann, José I. Martin-Subero, Stefan Gesk, Julia Hüsken, Maciej Giefing, Inga Nagel, Jennifer Riemke, Andreas Chott, Wolfram Klapper, Marie Parrens, Jean-Philippe Merlio, Ralf Küppers, Andreas Bräuninger, Reiner Siebert, Martin-Leo Hansmann   +14 more
doaj   +1 more source

Application of array comparative genomic hybridization in Korean children under 6 years old with global developmental delay [PDF]

Korean Journal of Pediatrics, 2017
PurposeRecent advancements in molecular techniques have greatly contributed to the discovery of genetic causes of unexplained developmental delay. Here, we describe the results of array comparative genomic hybridization (CGH) and the clinical features of
Kyung Yeon Lee, Eunsim Shin
doaj   +1 more source

A new case of de novo chromosome 19p13.12 deletion in an Omani girl with multiple congenital anomalies: a first case report from Oman

Journal of Biochemical and Clinical Genetics, 2018
Background: This report provides a molecular cytogenetic characterization of an Omani girl with 19p13.12 microdeletion and compares her clinical features of global developmental delay (GDD) and multiple congenital anomalies with the gene mutations and ...
Musallam Said Al-Araimi, Aliya Mahmood Al-Hosni, Ali Ahmed Al-Yahmadi, Salma Mohammed Al-Harasi   +3 more
doaj   +1 more source

Genomic profiling of submucosal-invasive gastric cancer by array-based comparative genomic hybridization. [PDF]

PLoS ONE, 2011
Genomic copy number aberrations (CNAs) in gastric cancer have already been extensively characterized by array comparative genomic hybridization (array CGH) analysis.
Akiko Kuroda, Yoshiyuki Tsukamoto, Lam Tung Nguyen, Tsuyoshi Noguchi, Ichiro Takeuchi, Masahiro Uchida, Tomohisa Uchida, Naoki Hijiya, Chisato Nakada, Tadayoshi Okimoto, Masaaki Kodama, Kazunari Murakami, Keiko Matsuura, Masao Seto, Hisao Ito, Toshio Fujioka, Masatsugu Moriyama   +16 more
doaj   +1 more source

Reporting Unwelcome Unanticipated Findings of Diagnostic Genomic Studies

Voices in Bioethics, 2014
The introduction of comparative genomic hybridization has revolutionized clinical genetics. It is used as a routine approach to the workup of developmental delays and multiple malformations.1-3 By subdividing chromosomes into their submicroscopic ...
Brian James Hanrahan, Robert Roger Lebel
doaj   +1 more source

Findings from ACGH in patient with psychomotor delay-case report

Genetics & Applications, 2019
Initial testing of children with psychomotor delays considers karyotype analysis and metabolic tests. However, introduction of Array Comparative Genomic Hybridization (ACGH) has become the standard method of diagnostics worldwide.
Vanja Vidović, Nela Maksimović, Tatjana Damnjanović, Biljana Jekić, Irina Milovac, Milka Grk, Stojko Vidović   +6 more
doaj   +1 more source

Investigation of marmoset hybrids (Cebuella pygmaea x Callithrix jacchus) and related Callitrichinae (Platyrrhini) by cross-species chromosome painting and comparative genomic hybridization [PDF]

, 2005
We report on the cytogenetics of twin offspring from an interspecies cross in marmosets (Callitrichinae, Platyrrhini), resulting from a pairing between a female Common marmoset (Callithrix jacchus, 2n = 46) and a male Pygmy marmoset (Cebuella pygmaea, 2n
Canavez FC, Dugoujon JM, G. Anzenberger, M. Münch, M. Neusser, Moore CM, Muller S, Muller S, Natori M, Pellicciari C, Ratomponirina C, Rosenberger AL, Rumpler Y, Rylands AB, S. Müller, Yunis E   +15 more
core   +1 more source