Results 31 to 40 of about 88,145 (306)
CAISMOV24, a new human low-grade serous ovarian carcinoma cell line
BMC Cancer, 2017 Background The spontaneous immortalization of primary malignant cells is frequently assigned to their genetic instability during in vitro culturing. In this study, the new epithelial ovarian cancer cell line CAISMOV24 was described and compared with its ...
Rodrigo Fernandes da Silva +8 more
doaj +1 more source
Comparative genomic hybridization identifies virulence differences in Streptococcus suis. [PDF]
PLoS ONE, 2014 Streptococcus suis is an important zoonotic pathogen. However, identification of virulent S. suis strains is complicated because of the high diversity of the species. Here we evaluated the genetic difference among S.
Han Zheng +8 more
doaj +1 more source
Comparative genomic hybridization for the diagnosis of melanoma [PDF]
European Journal of Plastic Surgery, 2009 Despite advancements in protocols, a subset of melanocytic lesions continues to pose diagnostic challenges. This is particularly true in the pediatric population where certain congenital nevi mimic melanoma. Recently, comparative genomic hybridization (CGH) has been utilized to support diagnoses of melanocytic lesions based on DNA copy number changes ...
Vanison, Christopher +2 more
openaire +2 more sources
Caryoscope: An Open Source Java application for viewing microarray data in a genomic context
BMC Bioinformatics, 2004 Background Microarray-based comparative genome hybridization experiments generate data that can be mapped onto the genome. These data are interpreted more easily when represented graphically in a genomic context.
Ball Catherine A +4 more
doaj +1 more source
Identification of genomic alterations in pancreatic cancer using array-based comparative genomic hybridization. [PDF]
PLoS ONE, 2014 BACKGROUND: Genomic aberration is a common feature of human cancers and also is one of the basic mechanisms that lead to overexpression of oncogenes and underexpression of tumor suppressor genes.
Jian-Wei Liang +11 more
doaj +1 more source
Genomic profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization. [PDF]
PLoS ONE, 2013 We designed a study to investigate genetic relationships between primary tumors of oral squamous cell carcinoma (OSCC) and their lymph node metastases, and to identify genomic copy number aberrations (CNAs) related to lymph node metastasis.
Shunichi Yoshioka +9 more
doaj +1 more source
Cellular Oncology, 2009 Breast phyllodes tumour (PT) is a rare fibroepithelial tumour. The genetic alterations contributing to its tumorigenesis are largely unknown. To identify genomic regions involved in pathogenesis and progression of PTs we obtained genome-wide copy number ...
Arno Kuijper +6 more
doaj +1 more source
Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs
BioTechniques, 2004 Fluorescent cis-platinum compounds that react with the N7 atom of guanine are useful for labeling nucleic acids in fluorescence hybridization applications.
Anton K. Raap +8 more
doaj +1 more source
, 2011 Objective To present the perinatal findings and molecular cytogenetic analysis of a rare chromosomal abnormality involving structural and numerical abnormalities of chromosome 18 Materials, Methods and Results A 36 year old woman, gravida 5, para 3 ...
CHEN, CHIH-PING;LIN, SHUAN-PEI;SU, YI-NING;CHEN, YANN-JANG;WU, PEI-CHEN;LEE, CHEN-CHI;WANG, WAYSEEN +1 more
core +1 more source
Specific loss of chromosomes 1, 2, 6, 10, 13, 17, and 21 in chromophobe renal cell carcinomas revealed by comparative genomic hybridization [PDF]
, 1994 We analyzed 19 chromophobe renal cell carcinomas by means of comparative genomic hybridization. Two tumors revealed no numerical abnormalities. In the remaining 17 cases we found loss of entire chromosomes with underrepresentation of chromosome 1 ...
Speicher, Michael R. +7 more
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