Results 1 to 10 of about 115,619 (257)

Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2019
Alkanethiolself-assembled monolayers (SAMs) with Peptide Nucleic Acid (PNA) were proposedas a novel probe design in electrochemical biosensors.
Zehra Banu Bahsi Oral
doaj   +1 more source

Affinity Purification of RNA: Sequence-Specific Capture by Nonionic Morpholino Probes

open access: yesBioTechniques, 1997
Nucleic acid isolation for amplification-based diagnostics requires techniques that do not co-purify inhibitors of DNA polymerases. Also, other requirements for an ideal sample preparation technology include ease of use, capability for automation, high ...
J.M. Wages   +4 more
doaj   +1 more source

Single-molecule tracking of the transcription cycle by sub-second RNA detection

open access: yeseLife, 2014
Transcription is an inherently stochastic, noisy, and multi-step process, in which fluctuations at every step can cause variations in RNA synthesis, and affect physiology and differentiation decisions in otherwise identical cells. However, it has been an
Zhengjian Zhang   +4 more
doaj   +1 more source

Nucleic acid analysis by sandwich hybridization

open access: yesJournal of Clinical Laboratory Analysis, 1989
AbstractOne of the most significant achievements of the biochemist during the past two decades is the use to which immunologically based assays have been put in clinical diagnosis (Hood et al.: Immunology, 1984). The problem faced and surmounted by immunologists in effecting the transition from research tool to routine clinical assay bears a remarkable
P J, Nicholls, A D, Malcolm
openaire   +2 more sources

New Uses for the Personal Glucose Meter: Detection of Nucleic Acid Biomarkers for Prostate Cancer Screening

open access: yesSensors, 2020
A personal glucose meter (PGM)-based method for quantitative detection of a urinary nucleic acid biomarker in prostate cancer screening, the so-called PCA3, is reported herein.
Clara Abardía-Serrano   +3 more
doaj   +1 more source

Detection of Circovirus in Foxes with Meningoencephalitis, United Kingdom, 2009–2013

open access: yesEmerging Infectious Diseases, 2015
A fox circovirus was identified in serum samples from foxes with unexplained neurologic signs by using viral metagenomics. Fox circovirus nucleic acid was localized in histological lesions of the cerebrum by in situ hybridization. Viruses from the family
Steve Bexton   +11 more
doaj   +1 more source

Hybrids of Nucleic Acids and Carbon Nanotubes for Nanobiotechnology [PDF]

open access: yesNanomaterials, 2015
Recent progress in the combination of nucleic acids and carbon nanotubes (CNTs) has been briefly reviewed here. Since discovering the hybridization phenomenon of DNA molecules and CNTs in 2003, a large amount of fundamental and applied research has been carried out.
openaire   +3 more sources

Detection of Common Bacterial Causes of STIs among STD Clinic Attendees by Gram Stain and Culture versus the Microarray Nucleic Acid Hybridization Method

open access: yesCentral Asian Journal of Medical Sciences, 2017
Objectives: The purpose of the study was to determine the prevalence and etiology of predominant sexually transmitted infections (STIs) occurring among the STD and Gynecology Clinic attendees and to compare sensitivity and specificity of conventional ...
Jugderjav Badrakh   +6 more
doaj   +1 more source

Impedimetric Sensing of Factor V Leiden Mutation by Zip Nucleic Acid Probe and Electrochemical Array

open access: yesBiosensors, 2020
A carbon nanofiber enriched 8-channel screen-printed electrochemical array was used for the impedimetric detection of SNP related to Factor V Leiden (FV Leiden) mutation, which is the most common inherited form of thrombophilia.
Arzum Erdem, Ece Eksin
doaj   +1 more source

Nucleic Acid-programmed Assemblies: Translating Instruction into Function in Chemical Biology

open access: yesCHIMIA, 2013
The predictability of nucleic acid hybridization offers an attractive platform to program the assembly of tagged ligands or reactants. Hybridization can be used to display multiple ligands in order to gain affinity and/or selectivity through the
Nicolas Winssinger
doaj   +1 more source

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