Results 11 to 20 of about 119,828 (299)

Nucleic Acid Analysis Using Multifunctional Hybridization Sensors

open access: yesProceedings, 2017
Hybridization of nucleic acid probes remains one of the most common strategies for sensing of [...]
Dmitry M. Kolpashchikov
doaj   +2 more sources

Diagnosis of plant viruses by nucleic acid hybridization

open access: yesAgricultural and Food Science, 1987
Nucleic acid hybridization is a powerful technique for the diagnosis of many plant viruses not easily detected by serological techniques. It is particularly effective in the detection of viruses occurring in low amount in plant tissue, viruses that are ...
Reijo Karjalainen   +2 more
doaj   +2 more sources

Protein-Based Anchoring Methods for Nucleic Acid Detection in Lateral Flow Format Assays

open access: yesMicromachines, 2023
The use of lateral flow assays to detect nucleic acid targets has many applications including point-of-care diagnostics, environmental monitoring, and food safety.
Kira Hallerbach   +6 more
doaj   +1 more source

Highly efficient and robust π-FISH rainbow for multiplexed in situ detection of diverse biomolecules

open access: yesNature Communications, 2023
Fluorescence in situ hybridization (FISH) methods with high sensitivity are needed. Here the authors develop multiplex πFISH rainbow to detect a range of biomolecules; they also combine this with the hybridization chain reaction to develop πFISH ...
Yingfeng Tao   +17 more
doaj   +1 more source

Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

open access: yesActa Pharmaceutica Sinica B, 2023
RNAs are involved in the crucial processes of disease progression and have emerged as powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of therapeutic RNA to the targeted location and precise detection of RNA markers ...
Mengnan Zhao   +8 more
doaj   +1 more source

Algorithms for Nucleic Acid Sequence Design [PDF]

open access: yes, 2010
Motivated by a growing field of research focused on programming function into biomolecules, we seek to decrease the cost of high-quality rational nucleic acid sequence design while increasing its versatility and availability.
Zadeh, Joseph N.
core   +1 more source

Microfluidic Chip for the Electrochemical Detection of MicroRNAs: Methylene Blue Increasing the Specificity of the Biosensor

open access: yesFrontiers in Chemistry, 2022
MicroRNAs (miRNAs) are biomarkers involved in biological processes that are released by cells and found in biological fluids such as blood. The development of nucleic acid-based biosensors has significantly increased in the past 10 years because the ...
Claire Poujouly   +7 more
doaj   +1 more source

Nucleic Acid Hybridization [PDF]

open access: yes, 2020
Abbreviations -- Preface -- 1. Introduction to nucleic acid hybridization -- Structure of nucleic acids -- Forces stabilizing DNA structure -- Mismatched base pairs -- Stability of nucleic acids -- Effects of pH -- Effects of temperature -- Renaturation and hybridization -- 2.
openaire   +3 more sources

Nucleic Acid Hybrids as Advanced Antibacterial Nanocarriers [PDF]

open access: yesPharmaceutics, 2020
Conventional antibiotic therapy is often challenged by poor drug penetration/accumulation at infection sites and poses a significant burden to public health. Effective strategies to enhance the therapeutic efficacy of our existing arsenal include the use of nanoparticulate delivery platforms to improve drug targeting and minimize adverse effects ...
Sybil Obuobi, Nataša Škalko-Basnet
openaire   +4 more sources

Physico-chemical foundations underpinning microarray and next-generation sequencing experiments [PDF]

open access: yes, 2013
Hybridization of nucleic acids on solid surfaces is a key process involved in high-throughput technologies such as microarrays and, in some cases, next-generation sequencing (NGS).
Carlon, E   +54 more
core   +1 more source

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