Results 111 to 120 of about 80,578 (289)

Familial Case of Pelizaeus-Merzbacher Disorder Detected by Oligoarray Comparative Genomic Hybridization: Genotype-to-Phenotype Diagnosis [PDF]

, 2017
Kimia Najafi, Roxana Kariminejad, Kaveh Hosseini, Moshtagh Azadeh, Gole Maryam Abbassi, Neda Sadatian, Masood Bazrgar, Ariana Kariminejad, Mohamad Hassan Kariminejad   +8 more
openalex   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Prenatal Diagnosis of Small Supernumerary Marker Chromosome 10 by Array-Based Comparative Genomic Hybridization and Microdissected Chromosome Sequencing. [PDF]

Biomedicines, 2021
Lebedev IN, Karamysheva TV, Elisaphenko EA, Makunin AI, Zhigalina DI, Lopatkina ME, Drozdov GV, Cheremnykh AD, Torkhova NB, Seitova GN, Vasilyev SA, Kashevarova AA, Nazarenko LP, Rubtsov NB.   +13 more
europepmc   +1 more source

PGD for a complex chromosomal rearrangement by array comparative genomic hybridization [PDF]

, 2011
Evelyne Vanneste, Cindy Melotte, Thierry Voet, Caroline Robberecht, Sophie Debrock, A. Pexsters, C. Staessen, Carla Tomassetti, Eric Legius, Thomas D’Hooghe, Joris Vermeesch   +10 more
openalex   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Data from A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer

, 2023
Ning Li, Sippy Kaur, Joel Greshock, Heini Lassus, Xiaomin Zhong, Yanling Wang, Arto Leminen, Zhongjun Shao, Xiaowen Hu, Shun Liang, Dionyssios Katsaros, Qihong Huang, Ralf Bützow, Barbara L. Weber, George Coukos, Lin Zhang   +15 more
openalex   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Phylogenomic analyses of all species of swordtail fishes (genus Xiphophorus) show that hybridization preceded speciation

Nature Communications
Hybridization has been recognized to play important roles in evolution, however studies of the genetic consequence are still lagging behind in vertebrates due to the lack of appropriate experimental systems.
Kang Du, Juliana Morena Bonita Ricci, Yuan Lu, Mateo Garcia-Olazabal, Ronald B. Walter, Wesley C. Warren, Tristram O. Dodge, Molly Schumer, Hyun Park, Axel Meyer, Manfred Schartl   +10 more
doaj   +1 more source

Genome‐wide array‐based comparative genomic hybridization analysis of pancreatic adenocarcinoma: Identification of genetic indicators that predict patient outcome [PDF]

, 2007
Panayiotis Loukopoulos, Tatsuhiro Shibata, Hiroto Katoh, Akiko Kokubu, Michiie Sakamoto, Ken Yamazaki, Tomoo Kosuge, Yae Kanai, Fumie Hosoda, Issei Imoto, Misao Ohki, Jyoji Inazawa, Setsuo Hirohashi   +12 more
openalex   +1 more source

Supplementary Data from Array-Based Comparative Genomic Hybridization Identifies <i>CDK4</i> and <i>FOXM1</i> Alterations as Independent Predictors of Survival in Malignant Peripheral Nerve Sheath Tumor [PDF]

, 2023
Jin‐Sheng Yu, Hrishikesh Deshmukh, Jacqueline E. Payton, Christopher Dunham, Bernd W. Scheithauer, Tarık Tihan, Richard A. Prayson, Abhijit Guha, Julia A. Bridge, Rosalie E. Ferner, Guy Lindberg, Rebecca J. Gutmann, Ryan J. Emnett, Lorena Salavaggione, David H. Gutmann, Rakesh Nagarajan, Mark A. Watson, Arie Perry   +17 more
openalex   +1 more source