Results 121 to 130 of about 88,145 (306)

Summary of the histological features and genomic changes in samples applied to the array-based comparative genomic hybridization.

, 2013
aCGH: array-based comparative genomic hybridization, qPCR: real-time quantitative PCR, nc: no change.
Kanako Shinjo (384945), Hiroharu Kobayashi (384946), Yoriko Yamashita (138912), Hiroshi Seko (384947), Shinya Toyokuni (138955), Hiroaki Kajiyama (35140), Takashi Takahashi (61576), Shinya Akatsuka (138906), Yasushi Yatabe (245392), Fumitaka Kikkawa (35145)   +9 more
core   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Array-Based Comparative Genomic Hybridization Analysis in Children with Developmental Delay/Intellectual Disability. [PDF]

Balkan J Med Genet, 2021
Türkyılmaz A, Geckinli BB, Tekin E, Ates EA, Yarali O, Cebi AH, Arman A.   +6 more
europepmc   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Comparative Genomic Hybridization to Microarrays in Fetuses with High-Risk Prenatal Indications: Polish Experience with 7400 Pregnancies. [PDF]

Genes (Basel), 2022
Kowalczyk K, Bartnik-Głaska M, Smyk M, Plaskota I, Bernaciak J, Kędzior M, Wiśniowiecka-Kowalnik B, Deperas M, Domaradzka J, Łuszczek A, Dutkiewicz D, Kozar A, Grad D, Niemiec M, Ziemkiewicz K, Magdziak R, Braun-Walicka N, Barczyk A, Geremek M, Castañeda J, Kutkowska-Kaźmierczak A, Własienko P, Jakubów-Durska K, Dębska M, Kucińska-Chahwan A, Kozłowski S, Mikulska B, Issat T, Roszkowski T, Nawara-Baran A, Runge A, Jakubiuk-Tomaszuk A, Kruczek A, Kostyk E, Pietras G, Limon J, Zwoliński J, Ochman K, Szajner T, Węgrzyn P, Wielgoś M, Sąsiadek M, Obersztyn E, Nowakowska BA.   +43 more
europepmc   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

A case report of 2 patients developing multiple Merkel cell carcinomas-using comparative genomic hybridization to elucidate tumor relationship. [PDF]

JAAD Case Rep, 2022
Lowenstein SE, Lohman ME, Yu SS.
europepmc   +1 more source

Development of a Normalization Algorithm for Array Comparative Genomic Hybridization

, 2007
基因體的變異是腫瘤生成發展的主因之一。已經有許多的研究證明DNA序列拷貝數的異常對癌症致病是有重大的相關性。比較基因體雜合微陣列(array CGH)是依據基因表現的微陣列晶片的技術所研發，其可以以高解析度找出染色體上序列拷貝數的變異。然而，由於array CGH先天上的特性，許多針對基因表現的資料所使用的分析工具，如資料正規化演算法，通常無法得到令人滿意的結果。在此我們闡述一個新的array CGH正規化演算法，其可以利用在array CGH實驗中，染色體上相鄰位置探針的相依性來提供精準的array ...
陳鴻毅, Chen, Hung-I Harry
core  

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Increased Diagnostic Yield of Array Comparative Genomic Hybridization for Autism Spectrum Disorder in One Institution in Taiwan. [PDF]

Medicina (Kaunas), 2021
Lee CL, Chuang CK, Tu RY, Chiu HC, Lo YT, Chang YH, Chen YJ, Chou CL, Wu PS, Chen CP, Lin HY, Lin SP.   +11 more
europepmc   +1 more source