Results 191 to 200 of about 265,128 (376)

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

Advanced Therapeutics, EarlyView.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam, Lu Yanjun, Bee Luan Khoo, Tongxu Si, Heng Zou, Mengsu Yang   +5 more
wiley   +1 more source

Uterine smooth muscle tumor analysis by comparative genomic hybridization: a useful diagnostic tool in challenging lesions

Modern Pathology, 2015
S. Croce, A. Ribeiro, C. Brulard, J. Noel, F. Amant, E. Stoeckle, Mojgan Devouassoux-Shisheborah, A. Floquet, L. Arnould, F. Guyon, F. Mishellany, D. Garbay, Tine Cuppens, M. Zikan, A. Leroux, E. Frouin, P. Duvillard, P. Terrier, I. Farré, I. Valo, G. MacGrogan, F. Chibon   +21 more
semanticscholar   +1 more source

Comparative Genomic Hybridization in Pineal Germ Cell Tumors [PDF]

, 2000
Christian Rickert, Ronald Simon, Markus Bergmann, Barbara Dockhorn‐Dworniczak, Werner Paulus   +4 more
openalex   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

Cytogenetic Aberrations in Primary and Recurrent Fibrolamellar Hepatocellular Carcinoma Detected by Comparative Genomic Hybridization [PDF]

, 2000
Ludwig Wilkens, Martin Bredt, Peer Flemming, Stefan Kubicka, J. Klempnauer, Hans Kreipe   +5 more
openalex   +1 more source

Topoisomerase I Inhibition in ETV4‐overexpressed Non‐Small Cell Lung Cancer Promotes Replication and Transcription Mediated R‐Loop Accumulation and DNA Damage

Advanced Science, EarlyView.
The oncogenic ETS factor ETV4 exerts a pleiotropic control over DNA replication both in a transcription‐dependent and ‐independent fashion in NSCLC cells. High‐ETV4 expression leads to R‐loop formation and DNA damage in response to TOP1 inhibition.
Jiaxi Zhang, Yan Wang, Shanhu Cao, Shelly M. Xie, Bei Liu, Yimeng Li, Yuqi Hou, Xue Meng, Mingzhu Ruan, Di Bu, Jia Kang, Ruxin Li, Lei Lou, Juan Wang, Lingxiao Xing   +14 more
wiley   +1 more source

Integrated sequencing and array comparative genomic hybridization in familial Parkinson disease. [PDF]

Neurol Genet, 2020
Robak LA, Du R, Yuan B, Gu S, Alfradique-Dunham I, Kondapalli V, Hinojosa E, Stillwell A, Young E, Zhang C, Song X, Du H, Gambin T, Jhangiani SN, Coban Akdemir Z, Muzny DM, Tejomurtula A, Ross OA, Shaw C, Jankovic J, Bi W, Posey JE, Lupski JR, Shulman JM.   +23 more
europepmc   +1 more source

Comparison of genetic changes in schistosome-related transitional and squamous bladder cancers using comparative genomic hybridization [PDF]

, 2000
Michael Muscheck, Hassan Abol‐Enein, Karen Chew, Dan H. Moore, Vivek Bhargava, Mohamed A. Ghoneim, Peter R. Carroll, Frederic M. Waldman   +7 more
openalex   +1 more source

The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots

Advanced Science, EarlyView.
DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya, Nikolai Davey, Pranjal Srivastava, Andrew Bender, Léo Pio‐Lopez, Douglas Hazel, Michael Levin   +6 more
wiley   +1 more source

Inconsistency of Karyotyping and Array Comparative Genomic Hybridization (aCGH) in a Mosaic Turner Syndrome Case. [PDF]

Glob Med Genet, 2020
Tulay P, Ergoren MC, Alkaya A, Yayci E, Sag SO, Temel SG.   +5 more
europepmc   +1 more source