Results 171 to 180 of about 449,093 (327)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

QuickProt: A Fast and Accurate Homology-Based Protein Annotation Tool for Non-Model Organisms to Advance Comparative Genomics. [PDF]

Mol Ecol Resour
Chen G, Du H, Cao Z, Wu Y, Zhang C, Zhou Y, Ao J, Sun Y, Yuan Z.   +8 more
europepmc   +1 more source

Transport capabilities of eleven gram-positive bacteria: Comparative genomic analyses

, 2007
Graciela L. Lorca, Ravi D. Barabote, Vladimir Zlotopolski, Can V. Tran, Brit Winnen, Rikki N. Hvorup, Aaron J. Stonestrom, Elizabeth Nguyen, Li-Wen Huang, David Kim, Milton H. Saier   +10 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Linking Comparative Genomics, Morphology and In Vitro Assays to Understand Deep Diving in Cetaceans. [PDF]

Mol Ecol
Thorstensen MJ.
europepmc   +1 more source

Interspecies Comparative Genomic Hybridization (I-CGH): A New Twist to Study Animal Tumor Models [PDF]

, 2007
Sivakumar Jaikumar, Zhengping Zhuang, Poonam Mannan, Alexander O. Vortmeyer, Makoto Furuta, Rob D. Dickerman, Julia Bedanova, Russell R. Lonser, Stuart Walbridge, Robert J. Weil, Victor V. Lobanenkov, Edward H. Oldfield, Svetlana Pack   +12 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Predicting bacterial-mediated entomopathogenicity through comparative genomics and statistical modeling. [PDF]

Microbiol Spectr
Yanez Ortuno D, Chen MY, McDonald K, Gacad A, Carrillo J, Haney CH.   +5 more
europepmc   +1 more source

Comparative genomics and evolutionary analysis of Lactococcus garvieae isolated from human endocarditis

, 2022
Carlos Francés‐Cuesta, Iván Ansari, José Francisco Fernández‐Garayzábal, Alicia Gibello, Fernando Gónzález‐Candelas   +4 more
openalex   +1 more source

Comparative genomic analysis revealed specific mutation pattern between human coronavirus SARS-CoV-2 and Bat-SARSr-CoV RaTG13 [PDF]

, 2020
Longxian Lv, Gaolei Li, Jinhui Chen, Xinle Liang, Yudong Li   +4 more
openalex   +1 more source